Phase 4
N=100
Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty
Osteoarthritis · Arthroplasty
Bottom Line
View on ClinicalTrials.gov: NCT02658149 ↗Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Apr 2018
Primary outcome: Primary: Pain Score at 3 Hours — 4.0; 2.9 units on a scale — p=0.036
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Ropivacaine with NaCl (Drug); Epinephrine (Drug); Morphine (Drug); Ketorolac Tromethamine (Drug); Ropivacaine (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Corewell Health East
- Primary completion
- May 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Score at 3 Hours |
4.0; 2.9 | 0.036 sig |
| SECONDARY Pain Score at 3-24 Hours |
1.9; 1.3 | 0.204 |
| SECONDARY Pain Score at 24-48 Hours |
1.9; 1.7 | 1.0 |
| SECONDARY Opioid Usage In-hospital at 24 Hours |
19.5; 16.7 | 0.741 |
| SECONDARY Opioid Usage In-hospital at 48 Hours |
22.3; 20.8 | 1.0 |
Summary
The primary objective of this study is to examine whether there is a difference in the level of resting pain following total hip arthroplasty with an anterior approach with use of a psoas compartment block versus a local periarticular anesthetic infiltration
Eligibility Criteria
Inclusion Criteria
- Patients undergoing unilateral primary total hip arthroplasty by Dr. James Verner at Beaumont Hospital Royal Oak
- Have a diagnosis of primary osteoarthritis (i.e. degenerative joint disease)
- Surgical approach is anterior
Exclusion Criteria
- Minors (age less than 18 years)
- Pregnant (surgically sterile, post-menopausal, or negative blood test)
- Previous ipsilateral hip surgery
- Lumbar instrumentation
- Acute trauma
- Rheumatoid arthritis
- Avascular necrosis
- Hip dysplasia
- Known sensitivity, allergy, or contraindication to anesthetics being used in the study
- Narcotic sensitivity
- History of over 6 months of opioid dependency prior to surgery (excluding tramadol)
- Peripheral neuropathy
- Mental/cognitive impairment that would interfere with the patient's self-assessments of function, pain, or quality of life
Data sourced from ClinicalTrials.gov (NCT02658149). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.