N/A N=84 Randomized Single-blind Treatment

Decreasing Postoperative Pain Following Endometrial Ablation

Postoperative Pain

Bottom Line

View on ClinicalTrials.gov: NCT02660918 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Aug 2019

Primary outcome: Primary: Postoperative Pain Score — 2.71; 1.44; 3.37; 2.81 units on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Bupivacaine (Drug); Normal Saline (Other)
Age: Adult · 30+ yrs
Sex: Female
Sponsor: Christiana Care Health Services
Primary completion: Mar 2017

Outcome Measures

Outcome	Result	p-value
PRIMARY Postoperative Pain Score	2.71; 1.44; 3.37; 2.81; 2.47; 2.24	—
PRIMARY Intraoperative Total Blood Loss	6.38; 7.15	—
PRIMARY Remaining Tylenol Tablets With Codeine Not Taken at the End of Day 1 Following Discharge	9.18; 8.74	—
SECONDARY Occurrence of Intraoperative Complication	0; 0; 0; 0; 2; 1	—
SECONDARY Postoperative Complication	0; 0; 1; 2; 0; 0	—
SECONDARY Postoperative Opioid Administered Following the Procedure But Prior to Discharge.	3; 1; 0; 0; 8; 6	—
SECONDARY Postoperative Toradol	36; 32	—
SECONDARY Postoperative Anti-emetic	2; 1; 6; 1; 0; 0	—
SECONDARY Time Between Recovery Initiation and Discharge	1.63; 1.59	—

Summary

To determine whether paracervical injection of long acting local anesthesia decreases postoperative pain following endometrial ablation under general anesthesia.

Eligibility Criteria

Inclusion Criteria

Premenopausal women
English as primary language
undergoing outpatient endometrial ablation at the Christiana Hospital Surgical Center
Indication of menorrhagia
Inication of abnormal uterine bleeding
Indication of thickened endometrium.

Exclusion Criteria

Known malignancy
weight less than 50 Kg
amide allergy
history of chronic pain
cardiac arrhythmia
dilaudid/codeine allergy
history of opioid use
inability to take opioids by mouth
uterine anomaly
previous endometrial ablation
primary language other than English.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02660918). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.