N/A N=20 Basic Science

Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain

Vertebral Artery Dissection · Cerebrovascular Accident · Stroke

Bottom Line

View on ClinicalTrials.gov: NCT02667821 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Sep 2017

Primary outcome: Primary: Changes in Blood Flow Through the Vertebral Artery and Posterior Cerebral and Cerebellar Circulation — 15.5; 15.1; 14.7 cm/s

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Head positions and spinal manipulation (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Canadian Memorial Chiropractic College
Primary completion: May 2017

Outcome Measures

Outcome	Result	p-value
PRIMARY Changes in Blood Flow Through the Vertebral Artery and Posterior Cerebral and Cerebellar Circulation	15.5; 15.1; 14.7	—
SECONDARY Changes in Tissue Perfusion in the Posterior Cerebrum and Cerebellum Will be Assessed Using Arterial Spin Labeling (ASL) MRI Technique.	79.2; 79; 80.1	—

Summary

The Investigators are performing a study to determine, in patients with chronic/recurrent neck pain, the cerebrovascular hemodynamic consequences of cervical spine movements, including manipulation, in vivo using fMRI technology on vertebral and cranial blood flow dynamics affecting brain perfusion, and extend the current data set on these variables

Eligibility Criteria

Inclusion Criteria

Adults aged 18 years and older with chronic/recurrent neck pain Grade II.
Must have been prescribed cervical spinal manipulation for treatment of their neck pain condition.

Exclusion Criteria

A history of neck pain with associated arm pain within the last 6 months
Any current or history of neurologic symptoms including facial or extremity weakness, abnormal sensation to the face, body, or extremities, uncontrolled movements, abnormal gait, dizziness, unexplained nausea/vomiting, difficulty with speaking or swallowing
History of new or severe (Visual Analogue Scale >6) headaches in the last 3 months
Any contraindications to MRI
Any history of using drugs that affect blood flow such as Warfarin, or anti-coagulants.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02667821). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.