N/A
Completed N=20
Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
Vertebral Artery Dissection · Cerebrovascular Accident · Stroke
Source: ClinicalTrials.gov NCT02667821 ↗
Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Sep 2017
Primary outcomePrimary: Changes in Blood Flow Through the Vertebral Artery and Posterior Cerebral and Cerebellar Circulation — 15.5; 15.1; 14.7 cm/s
Summary
The Investigators are performing a study to determine, in patients with chronic/recurrent neck pain, the cerebrovascular hemodynamic consequences of cervical spine movements, including manipulation, in vivo using fMRI technology on vertebral and cranial blood flow dynamics affecting brain perfusion, and extend the current data set on these variables
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Changes in Blood Flow Through the Vertebral Artery and Posterior Cerebral and Cerebellar Circulation |
15.5; 15.1; 14.7 | — |
| SECONDARY Changes in Tissue Perfusion in the Posterior Cerebrum and Cerebellum Will be Assessed Using Arterial Spin Labeling (ASL) MRI Technique. |
79.2; 79; 80.1 | — |
Eligibility Criteria
Inclusion Criteria
- Adults aged 18 years and older with chronic/recurrent neck pain Grade II.
- Must have been prescribed cervical spinal manipulation for treatment of their neck pain condition.
Exclusion Criteria
- A history of neck pain with associated arm pain within the last 6 months
- Any current or history of neurologic symptoms including facial or extremity weakness, abnormal sensation to the face, body, or extremities, uncontrolled movements, abnormal gait, dizziness, unexplained nausea/vomiting, difficulty with speaking or swallowing
- History of new or severe (Visual Analogue Scale >6) headaches in the last 3 months
- Any contraindications to MRI
- Any history of using drugs that affect blood flow such as Warfarin, or anti-coagulants.
Data sourced from ClinicalTrials.gov (NCT02667821). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.