N/A N=395 Prevention

Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Use Disorder

Opiate Antagonist Overdose · Opioid-Related Disorders

Bottom Line

View on ClinicalTrials.gov: NCT02669901 ↗

Enrolled (actual)

395

Serious AEs

0.0%

Results posted

Aug 2024

Primary outcome: Primary: To Measure the Association of Take-home Naloxone With Overdose Reversals Performed by Patients With Opioid Use Disorder Enrolled in an Opioid Treatment Program — 73; 263 Participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Naloxone Auto-Injector (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of New Mexico
Primary completion: May 2017

Outcome Measures

Outcome	Result	p-value
PRIMARY To Measure the Association of Take-home Naloxone With Overdose Reversals Performed by Patients With Opioid Use Disorder Enrolled in an Opioid Treatment Program	73; 263	—

Summary

The purpose of this pilot-study is to to distribute naloxone auto-injector in a "Universal Precaution" manner to patients with opioid substance use disorder. The objectives are to decrease the number of fatal and nonfatal overdose deaths, to examine and understand the risk factors for serious opioid toxicity and overdose, and to evaluate the unintentional opioid overdose risk utilizing an evidence-based screening questionnaire.

Eligibility Criteria

Inclusion Criteria

All patients treated with methadone, naltrexone or buprenorphine as medication assisted treatment at the UNM Addiction and Substance Abuse Program (UNM ASAP) aged 18 or older

Exclusion Criteria

Subjects who are allergic to naloxone and its inactive ingredients. Inactive ingredients include buffering agents.
Subjects younger than 18.
Subjects not being treated at UNM ASAP.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02669901). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.