30 closest matches · ranked by relevance
Opioid Withdrawal · Physical Dependence
Primary: Change in Objective Opioid Withdrawal Score (OOWS) From Baseline (Prevention of Opioid Withdrawal) — 3.6; 3.6 units on a scale — p=0.87
Narcotic Abuse
Primary: Abuse Liability Proxy — 0.197; 0.483; 0.159; 7.678 units on a scale (points 0-100) — p=<.05
Substance-Related Disorders
Primary: OOWS Score — 3.5; 1.0; 0 units on a scale (OOWS Scale) — p=0.0001
Naloxone
Primary: The Number of Participants That Completed the Training in 6 Months — 55; 56; 10; 9 Participants
Computer + Fluency · Computer Only · Treatment as Usual
Primary: Knowledge Gain — 30.6; 30.5; 27.56; 40.7 units on a scale
Hypogonadotropic Hypogonadism · Low Testosterone
Primary: Average Change in Mean Luteinizing Hormone (LH) Value — 1.571 IU/L
Chronic Pain · Opioid Induced Constipation
Primary: Incidence and Severity of Treatment Emergent Adverse Events on Single Dosing. — 8; 5; 4; 6 participants
Opioid Overdose
Primary: Rate of Fatal Opioid Overdose — 2; 6 Participants
Opiate Antagonist Overdose · Opioid-Related Disorders
Primary: To Measure the Association of Take-home Naloxone With Overdose Reversals Performed by Patients With Opioid Use Disorder Enrolled in an Opioid Treatment Program — 73; 263…
Opioid Dependence
Primary: Retention in Treatment — 7; 5; 6 participants — p=0.32
Opioid Dependence
Primary: Successful Naltrexone Initiation — 11 Participants
Chronic Low-back Pain
Primary: Mean Change in Subcortical Brain Structure Volume — 0.054; 0.74; 0.27; 0.48 cubic centimeters — p=>0.05
Neonatal Abstinence Syndrome
Primary: Finnegan Neonatal Abstinence Scoring System — 7.5; 8.5; 6.6; 5.7 scores on a scale
Surgery · Opioid Use
Primary: Unused Opioids — 5; 10 oxycodone 5mg tablets
Opiate Dependence
Primary: Slope Change From Baseline for Pupil Size — -0.5540; -0.3607; -0.1410 cm(2)/hr
Drug Overdose · Opioid-Related Disorders
Primary: Overdose Risk Behavior — -1.54; -0.51 Scores on a scale
Opioid-Use Disorder (OUD)
Primary: Frequency of Positive Urine Tests at 30 Days (Chart Review) — 35; 45; 1; 0 Participants
Substance-Related Disorders
Primary: Brain Regions With Increases or Decreases in Amplitude of Low Frequency Fluctuations (ALFF) Associated With Ondansetron Administration — 0.519; 0.562; 0.478; 0.486…
Opioid Overdose
Primary: Change in Minute Ventilation 5 Minutes From Opioid Induced Nadir — 4.42; 2.03 L/min
Opioid Abuse · Opioid Dependence · Opioid-Related Disorders
Primary: Change in Subjective Response to Oxycodone Measured With 100 Millimeter Visual Analog Scale — -13.81; -9.67 units on a scale
Moderate or Severe Opioid Use Disorder
Primary: Treatment Phase Drug Liking Visual Analog Scale (VAS) Emax Scores for Baseline and Four Challenge Sessions Compared to Baseline (Completer Population) for CAM2038 q1w…
Constipation Drug Induced
Primary: Occurrence of Bowl Movement — 2; 2; 5 Participants
Opioid Dependence · Opioid Withdrawal
Primary: Area Under the Curve (AUC) in COWS Total Score on Days 1 to 5 Inclusive — 4.2; 3.4 Average COWS score * hours
Stable Opioid Dependence
Primary: Successful Discontinuation of Buprenorphine — 6 Participants
Opioid-use Disorder
Primary: Successful Vivitrol Induction — 10 Participants
Alcohol Drinking · Opioid Use, Unspecified
Primary: Change in Brain Activation to Reward Between Placebo and Active Medication — 0.25; 0.26 percentage signal change
Opioid-Related Disorders · Drug Overdose
Primary: Number of Overdose Events — 0; 0 overdoses
Substance Withdrawal Syndrome
Primary: Number of Participants That Received Rescue Medication for Withdrawal Symptoms Within 1 Hour — 9; 19 Participants
Coronary Artery Disease
Primary: Platelet Reactivity Measured by VerifyNow P2Y12 — 130; 97 PRU — p=0.261
Substance Withdrawal Syndrome
Primary: Description of Signs and Symptoms of OIWS in Patients Who Scored Positive for Withdrawal Syndrome (OIWS) According to Diagnostic and Statistical Manual of Mental…