Phase 4
Completed N=60
Geriatric Ketamine for Pain Management Study
Source: ClinicalTrials.gov NCT02673372 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
May 2019
Primary outcomePrimary: Reduction of Pain Score at 30 Minutes — 4.4; 4.2 score on a scale
◆ Published Evidence
Established
79citations · ~11 / year
Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled trial.
Summary
This research project is geared towards geriatric analgesia in the Emergency Department (ED) with a goal of reducing the administration of opioid pain medications to elderly patients, thereby avoiding the commonly occurring, severe side effects associated with such medications, including hypotension, respiratory depression, altered mental status, delirium, as well as nausea/vomiting and constipation.
The primary outcome of the study will be difference in pain score from baseline to 30 minutes post-medication administration.
This project has the potential to change and modify the ED approach to geriatric analgesia by virtue of minimizing the use of opioid administration in elderly patients. T
Linked Publications
-
Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Reduction of Pain Score at 30 Minutes |
4.4; 4.2 | — |
Eligibility Criteria
Inclusion Criteria
- ED patients; 65 years of age and older; abdominal, flank, back, traumatic chest, neck or musculoskeletal pain; capacity to give verbal or written consent.
Exclusion Criteria
- ED patients 115kg, unstable vital signs (systolic blood pressure 180 mmHg; heart rate 150 beats per minute; and respirations 30 per minute), and past medical history of severe renal or hepatic insufficiency, alcohol or drug abuse or psychiatric illness; Patients with BMI>40; severe COPD
Data sourced from ClinicalTrials.gov (NCT02673372) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.