N/A N=32 Randomized Double-blind Basic Science

The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

Antisocial Behavior · Aggression

Bottom Line

View on ClinicalTrials.gov: NCT02674516 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2022

Primary outcome: Primary: Number of Pins Inserted Into a Virtual Voodoo Doll After 48 Hours — 3.77; .64 pins

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Transcranial direct current stimulation (Device); Sham transcranial direct current stimulation (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Pennsylvania
Primary completion: Jun 2020

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Pins Inserted Into a Virtual Voodoo Doll After 48 Hours	3.77; .64	—

Summary

This study investigates the relationship between prefrontal cortex activity and antisocial and aggressive behavior, and risk factors for such behavior. In the double-blind, randomized controlled trial, participants will undergo three sessions of anodal transcranial direct current stimulation of the dorsolateral prefrontal cortex or sham stimulation and complete survey and laboratory measures assessing antisocial behavior and risk factors. Heart rate and skin conductance will also be measured.

Eligibility Criteria

Inclusion Criteria

Above 18 years of age
Able to understand the nature of the study and give informed consent

Exclusion Criteria

Currently consuming anti-convulsant, anti-psychotic, or sedative/hypnotic medications
Currently consuming anti-depressants
History of seizures
Metallic implants on the scalp
Participation in other transcranial magnetic stimulation (TMS) or tDCS experiments on the same day
History of adverse reactions to tDCS

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02674516). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.