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N/A N=15 Randomized Single-blind Treatment

Blue Blockers at Night and Insomnia Symptoms

Insomnia · Sleep

Enrolled (actual)
15
Serious AEs
0.0%
Results posted
Jul 2019
Primary outcome: Primary: Pittsburgh Insomnia Rating Scale-65 (PIRS65) Total Score — 72.64 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Blue blocking (BB) lenses (Device); Clear lenses (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Columbia University
Primary completion
Mar 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Pittsburgh Insomnia Rating Scale-65 (PIRS65) Total Score
88.93
PRIMARY
Pittsburgh Insomnia Rating Scale-65 (PIRS65) Total Score
88.93
SECONDARY
Sleep Efficiency (Time Spent Asleep Divided by Total Time in Bed) Determined With Wrist-worn Accelerometry
77.01
SECONDARY
Sleep Efficiency (Time Spent Asleep Divided by Total Time in Bed) Determined With Wrist-worn Accelerometry
77.01

Summary

Under entrained conditions, humans maintain a consolidated nocturnal sleep episode that coincides with environmental darkness and endogenous melatonin secretion. Various factors, such as artificial light, can compromise this temporal harmony, resulting in sleep disruption. Light is the strongest synchronizer of the circadian clock, with direct inputs via the retinohypothalamic tract to brain centers regulating sleep and circadian rhythms. Evening light exposure can suppress melatonin secretion and worsen sleep. This is critical, since most individuals routinely expose themselves to light before bedtime. The high sensitivity of the circadian system to blue wavelength light indicates that modern light sources such as light-emitting diodes (LED) may have particularly deleterious effects on sleep. It is possible to selectively filter out blue light while maintaining other visible spectra with blue-blocking (BB) lenses. Wearing BB lenses before bedtime may present a simple, affordable, and safe method to improve sleep. None have yet investigated the effects of BB lenses on subjective and objective sleep in insomnia patients, while simultaneously exploring the effects on melatonin secretion.

Eligibility Criteria

Inclusion Criteria

  • Insomnia for at least 1 month based on Insomnia Symptoms Questionnaire

Exclusion Criteria

  • obstructive sleep apnea; narcolepsy; periodic leg movement disorder
  • currently shift worker
  • psychiatric or neurologic disorders
  • deep vein thrombosis
  • current cigarette smoker
  • currently taking beta-blockers
  • pregnant/breastfeeding
  • children less than 1 year old at home
  • excessive daily caffeine intake
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02698800). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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