N/A
Completed N=100
Supportive and Supportive-Expressive Treatment for Depression
Source: ClinicalTrials.gov NCT02728557 ↗Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Jan 2025
Primary outcomePrimary: Hamilton Rating Scale for Depression (HRSD) — 12.32; 12.06; 20.20; 20.08 units on a scale — p=.016
Summary
This study will assign patients to two types of psychotherapies in treating people with a major depression disorder, expressive versus supportive techniques, and will examine their ability to benefit from treatment based on their attachment orientation. This is a four month protocol, with a year follow up period, will compare patients receiving supportive-expressive treatment with either expressive focus or supportive focus.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Hamilton Rating Scale for Depression (HRSD) |
12.32; 12.06; 20.20; 20.08 | .016 sig |
| SECONDARY Beck Depression Inventory (BDI) |
16.62; 13.36; 27.55; 25.76 | — |
| SECONDARY Outcome Questionnaire (OQ) |
32.26; 26.33; 73.435; 69.519 | — |
Eligibility Criteria
Inclusion Criteria
- Meeting MDD diagnostic criteria using the structured clinical interviews for DSM-V and scoring more than 14 on the 17-item Hamilton rating scale for depression at two evaluations (one week apart).
- If on medication, patients' dosage must be stable for at least three months prior to entering the study, and they must be willing to maintain stable dosage for the duration of treatment
- Age between 18 and 60
- Hebrew language fluency
- Provision of written informed consent.
Exclusion Criteria
- Current risk of suicide or self-harm
- Current substance abuse disorders
- Current or past schizophrenia or psychosis, bipolar disorder, or severe eating disorder requiring medical monitoring
- History of organic mental disease
- Currently in psychotherapy
Data sourced from ClinicalTrials.gov (NCT02728557). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.