N/A
Completed N=159
Single Shot vs 24hr vs 48hr Continuous Adductor Canal Block After TKA
Total Knee Arthroplasty · Osteoarthritis · Post Operative Pain Control
Source: ClinicalTrials.gov NCT02730728 ↗
Enrolled (actual)
159
Serious AEs
0.0%
Results posted
Jun 2018
Primary outcomePrimary: Patients With Severe Pain at 48 Hours After Surgery — 21; 14; 12 percentage of patients with severe pain
Summary
The purpose of this study is to compare a single shot block, 24 hours, and 48 hour continuous catheter nerve block done via the adductor canal method in adult patients who have under gone total knee arthroplasty. Visual analogue scores, opioid consumption, time to up and go, ambulation, manual muscle tests, and Tinetti scores up to 72 hours post operatively will be used for comparison.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patients With Severe Pain at 48 Hours After Surgery |
21; 14; 12 | — |
| SECONDARY Pain Scores at 48 Hours After Surgery |
5; 4.3; 3.9 | — |
| SECONDARY Functional Recovery After Surgery |
155; 150; 200 | — |
| SECONDARY Patient-oriented Outcomes |
12; 13; 13 | — |
Eligibility Criteria
Inclusion Criteria
- Patients scheduled for primary total knee arthroplasty
- American Society of Anesthesiologists (ASA) physical status I -III
- mentally competent and able to give consent for enrollment in the study
Exclusion Criteria
- Patient younger than 18 years old
- Allergy to local anesthetics, systemic opioids (fentanyl, morphine, hydromorphone, and any of the drugs included in the multimodal perioperative pain protocol (MP3)
- Revision surgery
- Impaired kidney functions and patient with coagulopathy
- Chronic pain syndromes; Patients will be defined to have chronic pain if they are using regular daily doses of systemic narcotics for the past 3 months prior to the surgery
- BMI of 40 or more
- Pregnancy (positive urine pregnancy test result in Preop area on morning of surgery)
Data sourced from ClinicalTrials.gov (NCT02730728). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.