N/A
N=99
Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders
Alcohol Use Disorder
Bottom Line
View on ClinicalTrials.gov: NCT02742246 ↗Enrolled (actual)
99
Serious AEs
16.2%
Results posted
Mar 2023
Primary outcome: Primary: Percentage of Days Abstinent From Alcohol Use During Treatment as Measured by Timeline Follow Back — 49.26; 53.73; 47.57; 63.25 percentage of days abstinent — p=0.11
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Individual clinician-provided CBT (Behavioral); CBT4CBT (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Yale University
- Primary completion
- Dec 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Days Abstinent From Alcohol Use During Treatment as Measured by Timeline Follow Back |
49.26; 53.73; 47.57; 63.25; 69.93; 71.07 | 0.11 |
| PRIMARY Percentage of Days Abstinent From Alcohol Use During 6-month Follow-up Period as Measured by Timeline Follow Back |
69.26; 68.10; 73.28; 66.71; 75.86; 74.74 | 0.14 |
Summary
Evaluate the efficacy of CBT4CBT and clinician-delivered CBT relative to standard treatment for reducing alcohol use
Eligibility Criteria
Inclusion Criteria
Individuals will be included who:
- Are 18 years of age or older.
- Are applying for outpatient alcohol treatment and meet current DSM-5 criteria for alcohol use disorder, consuming at least 14/7 drinks (men/women) per week with at least 4 heavy drinking days reported in the past 28 days,
- Are sufficiently stable for 8 weeks of outpatient treatment and can commit to a 6-month follow-up
- Are willing to provide locator information for follow-up, and
- Are fluent in English and have a 6th grade or higher reading level.
Exclusion Criteria
Individuals will be excluded who:
- Have an untreated bipolar or schizophrenic disorder,
- Have a current legal case pending such that incarceration during the 8-week protocol is likely,
- Have been prescribed an alcohol pharmacotherapy (e.g., disulfiram, naltrexone) within the past two weeks, or
- Are physically dependent on alcohol, opioids or benzodiazepines such that immediate medical detoxification is necessary for safety purposes (individuals demonstrating significant withdrawal symptoms would be eligible for re-screening following brief medical detoxification, which is arranged by RCS staff at triage).
Data sourced from ClinicalTrials.gov (NCT02742246). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.