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N/A N=800 Randomized Single-blind Treatment

Suicide Prevention Intervention for At-Risk Individuals in Transition

Suicide

Enrolled (actual)
800
Serious AEs
51.3%
Results posted
Dec 2025
Primary outcome: Primary: Suicide Events — 1.8; 3.0 number of events

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Safety Planning Intervention (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Michigan State University
Primary completion
Dec 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Suicide Events
1.8; 3.0
SECONDARY
Suicide Attempts
1; 2.1
SECONDARY
Weeks of Active Suicide Ideation
9; 10.9
SECONDARY
Severity of Suicide Ideation
15.2; 16.2
SECONDARY
Time to First Suicide Event
7.4; 4.4
SECONDARY
Psychiatric Symptoms
44.1; 45
SECONDARY
Functioning
72; 72.3
SECONDARY
Treatment Utilization
9.02; 8.41
SECONDARY
Suicide-related Problem-solving
65.82; 65.39
SECONDARY
Belongingness
19.90; 20.08

Summary

The four year SPIRIT Trial, or Suicide Prevention Intervention for at-Risk Individuals in Transition, will recruit 800 pretrial jail detainees at risk for suicide. Each participant will be randomly assigned to today's standard care or to Safety Planning Intervention (SPI) method and then followed for one year after release. Outcomes include suicide events, suicide attempts and ideation, psychiatric symptoms, functioning, treatment utilization, problem-solving, belongingness, and cost-effectiveness.

Eligibility Criteria

Inclusion Criteria

  • Unsentenced male and female pretrial jail detainees
  • 18+ years of age
  • at risk for suicide, operationalized as a response of "yes" on item 4 or greater on the initial 5 C-SSRS screening questions, indicating the presence of at least some active suicide ideation with some intent to act in the past month (i.e., individuals at higher risk, such as those who report intent with specific plan and/or suicide attempt/s in the last month, will also be included);
  • speak and understand English well enough to understand questionnaires when they are read aloud.

Exclusion Criteria

  • expects to be sentenced and serve their sentence before being released to the community
  • cannot provide the name and contact information of at least two locator persons
  • does not have access to any telephone.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02759172). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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