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Home › Conditions › Suicide

Suicide

Subtypes of Suicide

Suicidal Ideation 10 Suicide attempt 2

30 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Suicide

64 trials tracked for Suicide: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 120 citations.

64Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 1 Phase 2 2 Other / NA 61
  1. Phase 4 Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder Completed · 120 cited
  2. Phase 2 Ketamine for Depression and Suicide Risk Completed
  3. Phase 2 Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents Completed
  4. N/A Southwest Hub for American Indian Youth Suicide Prevention Research Completed
  5. N/A Mindfulness-Based Cognitive Therapy for Suicide Prevention Completed
  6. N/A Developing Text-based Support for Parents of Adolescents After an Emergency Department Visit Completed
Show 44 more trials
  1. N/A Family Safety Net - Aim 3: Randomized Control Trial Completed
  2. N/A Suicide Safety Planning Group Treatment: "Project Life Force" Completed
  3. N/A Peer Based Suicide Prevention Completed
  4. N/A Technology-Assisted Systems Change for Suicide Prevention Completed
  5. N/A SAFER: A Brief Intervention Involving Family Members in Suicide Safety Planning Completed
  6. N/A Increasing Treatment Seeking Among Suicidal Veterans Calling the Crisis Line Completed
  7. N/A ACT for Life: a Brief Intervention for Maximizing Recovery After Suicidal Crises Completed
  8. N/A Veterans Coping Long-term With Active Suicide Completed
  9. N/A Drivers of Suicide Mobile App Study Completed
  10. N/A Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms Completed
  11. N/A Preventing Addiction Related Suicide (PARS) Completed
  12. N/A Window to Hope-Evaluating a Psychological Treatment for Hopelessness Among Veterans With Traumatic Brain Injury Completed
  13. N/A Effectiveness and Implementation of eScreening in Post 9/11 Transition Programs Completed
  14. N/A Suicide Prevention for Sexual and Gender Minority Youth (Case Series) Completed
  15. N/A Circle of Life. Improving Capacity of Swampy Cree Community Members to Recognize People at Risk for Suicide Completed
  16. N/A CAMS-RAS: for Suicide Prevention Completed
  17. N/A Adaptive Implementation Intervention for VA Suicide Risk Identification Strategy Completed
  18. N/A Nurse Suicide: Physiologic Sleep Health Promotion Trial Completed
  19. N/A A Digital Game Targeting Suicide Prevention in Adolescents Who Report Substance Misuse Completed
  20. N/A Suicide Prevention Intervention for Vulnerable Emerging Adult Sexual Minorities Completed
  21. N/A eLearning for Suicide Prevention Completed
  22. N/A 5 Alpha Reductase Inhibitors And The Risk Of Suicide And Depression Completed
  23. N/A Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop Completed
  24. N/A Pilot of Training on 988 and Narcan Completed
  25. N/A Pilot RCT of a Video-based Intervention for Suicide Prevention Completed
  26. N/A Developing a Mobile Intervention to Reduce Suicidal Cognitions in Veterans Completed
  27. N/A Crisis Line Facilitation Completed
  28. N/A PracticeGround: Transforming Training and Delivery of Mental Health EBPs Completed
  29. N/A Development of a Video-based Intervention for Suicide Prevention Completed
  30. N/A Trauma Survivors Outcomes and Support Study IV Completed
  31. N/A Emergency Room Firearm and Medication Safety Intervention Completed
  32. N/A Coping Long Term With Attempted Suicide - Adolescents Completed
  33. N/A Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT Completed
  34. N/A Patient and Provider Outcomes of E-Learning Training in Collaborative Assessment and Management of Suicidality Completed
  35. N/A CAMPUS - Feasibility Sub-Study Completed
  36. N/A Concurrent Treatment for Depressed Parents and DepressedAdolescents Completed
  37. N/A Digital Youth-Nominated Support Team (YST) Program Completed
  38. N/A Cognitive Behavioral Suicide Prevention for Psychosis: Aim 1 Completed
  39. N/A "Safety in Dementia": An Online Caregiver Intervention Completed
  40. N/A An Adaptive Intervention for Adolescents at Risk for Suicide: A Pilot SMART Completed
  41. N/A Practice Experiences for School Reintegration Completed
  42. N/A TMS for Suicidal Crisis in Active Duty SMs Completed
  43. N/A Developing Adaptive Interventions for Suicidal College Students Seeking Treatment - SMART Completed
  44. N/A Suicide Prevention for Sexual and Gender Minority Youth (Open Trial) Completed

Showing the 50 most-cited and recently-updated of 64 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
GLP-1R exposure shows no causal link to most mental disorders except eating disorders
Psychiatry Meta-analysis
GLP-1R exposure shows no causal link to most mental disorders except eating disorders GLP-1 Receptor Agonists Show Mixed Links to Mental Health
This meta-analysis investigated the causal associations between GLP-1 receptor agonists and various mental health outcomes including anxiety…
New research explores how GLP-1 receptor agonists relate to conditions like anxiety and depression, finding no clear genetic link to most di…
Jun 15, 2026
Five core domains of suicide postvention were identified through a Delphi consensus process
Psychiatry Guideline
Five core domains of suicide postvention were identified through a Delphi consensus process Experts agree on core pillars to support suicide survivors
This guideline based on a Delphi consensus study identifies five core domains for suicide postvention: impact/foundations, immediate respons…
A new framework identifies five key areas of care to help people and communities heal after a suicide.
Frontiers Jun 12, 2026
Narrative review highlights distinct biological processes in pediatric suicidal behavior compared to adults
Pediatrics Sys. Review
Narrative review highlights distinct biological processes in pediatric suicidal behavior compared to adults Biological markers of youth suicide differ from adults
This narrative review examines biological signatures of suicidal ideation, suicide attempts, and death by suicide in pediatric and adolescen…
A review suggests biological signs of suicidal thoughts in children and teens are distinct from adults, meaning adult data cannot explain yo…
Frontiers May 28, 2026
Narrative review links NRXN1 genetic variations to schizophrenia, autism, and other neuropsychiatric disorders
Neurology Sys. Review
Narrative review links NRXN1 genetic variations to schizophrenia, autism, and other neuropsychiatric disorders New research explains how one gene causes many brain disorders
This narrative review examines the association between NRXN1 genetic variations and a spectrum of neuropsychiatric disorders including schiz…
A single gene variation may explain why schizophrenia and autism often appear together, offering new hope for understanding these complex br…
Frontiers May 13, 2026
Multimodal stepped-prevention program fails to reduce suicidal thoughts in adolescents
Psychiatry RCT
Multimodal stepped-prevention program fails to reduce suicidal thoughts in adolescents Depression Prevention Program Fails to Reduce Suicidal Thoughts in Teens
This cluster RCT in 1593 adolescents from 15 Dutch high schools found that a multimodal stepped-prevention program did not reduce suicidal t…
A school-based program to prevent depression and suicide in teens did not reduce symptoms and may have increased them, possibly due to COVID…
medRxiv May 7, 2026
Analysis of 247,657 reports identifies central nervous system medications with suicide-related adverse event signals
Psychiatry Cohort
Analysis of 247,657 reports identifies central nervous system medications with suicide-related adverse event signals Researchers find central nervous system drugs associated with suicide reports
This cohort study analyzed 247,657 reports from the U.S.
Central nervous system medications showed the strongest link to suicide events in over two hundred thousand FDA reports.
Frontiers Apr 29, 2026
Retrospective case-case study links interpersonal trauma exposure to younger suicide deaths and distinct genetic profiles
Psychiatry
Retrospective case-case study links interpersonal trauma exposure to younger suicide deaths and distinct genetic profiles People with trauma histories die by suicide at younger ages
This retrospective case-case study analyzed 8,738 suicide deaths to compare individuals with and without interpersonal trauma exposure.
A study of over 8,700 suicide deaths found those with interpersonal trauma histories died younger and had different genetic and clinical pro…
medRxiv Apr 22, 2026
Cross-sectional evaluation finds supervisory system improves suicide risk detection in LLMs
Psychiatry
Cross-sectional evaluation finds supervisory system improves suicide risk detection in LLMs AI Chatbots Often Miss Suicide Risk. A New Safety Layer Could Change That
A cross-sectional evaluation of 224 paired suicide-related clinical vignettes compared an independent supervisory safety architecture with a…
Adding a separate safety monitor to AI chatbots could prevent them from missing signs of suicide risk, making digital mental health tools sa…
medRxiv Apr 22, 2026
Case-control study links impaired decision-making tasks to suicide attempts in depressed patients
Psychiatry Case-Control
Case-control study links impaired decision-making tasks to suicide attempts in depressed patients Can't weigh risks and rewards? Suicide attempters show different decision-making patterns
This case-control study assessed 132 depressed patients with suicide attempts, patient controls, and healthy controls using clinical decisio…
People who attempted suicide weigh risks differently, showing less fear of loss and more impulsive errors that link directly to higher suici…
Frontiers Apr 19, 2026
Survey examines suicidal ideation and behaviors among U.S. high school students
Infectious Disease
Survey examines suicidal ideation and behaviors among U.S. high school students Survey examines suicidal thoughts and behaviors among U.S. high school students
An observational survey report describes suicidal ideation and behaviors among high school students in the United States.
A recent survey of U.S. high school students examined their experiences with suicidal thoughts and behaviors, highlighting ongoing research …
CDC Apr 6, 2026
Observational study finds association between violence/harassment and suicidal ideation in transgender women
Infectious Disease
Observational study finds association between violence/harassment and suicidal ideation in transgender women Study explores link between violence, harassment and suicidal thoughts in transgender women
An observational study of transgender women in seven U.S.
Transgender women facing violence or harassment show higher rates of suicidal thoughts, though strong social support may help lessen this li…
CDC Apr 5, 2026
Survey examines mental health, suicide risk, and protective factors in US high school students
Psychiatry
Survey examines mental health, suicide risk, and protective factors in US high school students What protects high school students' mental health? A new survey looks for answers
A US survey report describes mental health and suicide risk among high school students, along with health-promoting behaviors and protective…
A new survey shifts focus from teen mental health crises to the everyday habits and relationships that might be protecting high school stude…
CDC Apr 3, 2026

All Suicide Articles