N/A
Completed N=979
Change the Cycle: An RCT to Prevent Injection Initiation
Substance Abuse, Intravenous · HIV · Heroin Dependence · opioid dependence
Source: ClinicalTrials.gov NCT02774954 ↗
Enrolled (actual)
979
Serious AEs
0.0%
Results posted
Mar 2023
Primary outcomePrimary: People Initiated Into Injection Drug Use — 2.05; 3.26 People initiated — p=0.35
Summary
The study will test the efficacy of a hour long, one-on-one, active listening counseling session (called Change the Cycle or CTC) aimed at reducing behaviors among active people who inject drugs (PWID) that research has found to facilitate uptake of injection drug use among non-injectors. The study will involve ~1,100 PWID who will be randomized to CTC or an equal attention control intervention on improving nutrition. Participants will be recruited in Los Angeles and San Francisco, California and followed up at 6 and 12 months to determine changes in direct and indirect facilitation of injection initiation among non-injectors.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY People Initiated Into Injection Drug Use |
2.05; 3.26 | 0.35 |
| PRIMARY Number of Request to Initiate Someone Into Drug Injection |
6.42; 4.06 | 0.35 |
Eligibility Criteria
Inclusion Criteria
- Self-reported Injection an illicit drug in the last 30 days,
- visible evidence of injection such as track mark or stigmata,
- at least 18 years of age
Exclusion Criteria
- Under 18 years of age,
- no self-reported drug injection in the last 30 days,
- no physical evidence of recent drug injection.
Data sourced from ClinicalTrials.gov (NCT02774954). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.