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Phase 4 Completed N=155 Randomized Double-blind Treatment

Adductor Canal Block Versus Periarticular Bupivicaine Injection in Total Knee Arthroplasty

Source: ClinicalTrials.gov NCT02777749 ↗
Enrolled (actual)
155
Serious AEs
0.0%
Results posted
Mar 2019
Primary outcomePrimary: Change in VAS Pain Scores — 3.0; 3.0; 2.7; 3.9 scores on a scale
◆ Published Evidence
No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

The objective of the study is to compare the efficacy of adductor canal blocks versus periarticular bupivacaine injections for pain management in total knee arthroplasty. This randomized clinical trial will compare outcomes between adductor canal blocks, periarticular bupivacaine injections, and periarticular liposomal bupivacaine injections. Results from this study will help determine the most appropriate perioperative pain management strategy for patients undergoing a total knee arthroplasty.

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in VAS Pain Scores
3.0; 3.0; 2.7; 3.9; 3.8; 3.0
SECONDARY
Change in Activity Level
26; 68; 65; 124; 120; 139
SECONDARY
Opioid Consumption
131; 100; 98; 33; 31; 35
SECONDARY
Range of Knee Flexion
99; 104; 101
SECONDARY
Length of Hospital Stay
2.9; 2.5; 2.5

Eligibility Criteria

Inclusion Criteria

  • Patients undergoing an unilateral primary total knee arthroplasty under the care of the two senior arthroplasty surgeons.

Exclusion Criteria

  • Allergy to bupivicaine or liposomal bupivicaine.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02777749). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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