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N/A Completed N=208 Randomized Treatment

Research on Expecting Moms and Sleep Therapy

Source: ClinicalTrials.gov NCT02805998 ↗
Enrolled (actual)
208
Serious AEs
0.0%
Results posted
Jun 2024
Primary outcomePrimary: Change in Insomnia Severity Index Scale Score — -6.054945; -2.212766 units on a scale

Summary

The overarching goal is to utilize a randomized control design to examine efficacy of web-based cognitive behavior therapy (CBT-I) plus treatment as usual compared to treatment as usual alone for insomnia and depression outcomes among pregnant women with insomnia at high risk for depressive relapse/recurrence (n=208).

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Insomnia Severity Index Scale Score
-6.054945; -2.212766
SECONDARY
Change in Percentage of Sleep Efficiency, as Determined by Daily Sleep Logs
8.25317; .3224638
SECONDARY
Change in Sleep Duration, as Determined by Daily Sleep Logs
.3426204; -.0230307
SECONDARY
Change in Global Sleep Quality, as Determined by Pittsburgh Sleep Quality Index Score
-3.172414; -.1595745
SECONDARY
Change in Depression Symptom Severity, as Determined by Edinburgh Postnatal Depression Scale Score
-2.224719; -.0425532
SECONDARY
Change in Insomnia Diagnosis, as Determined by Sleep Condition Indicator
-.5955056; -.2021277

Eligibility Criteria

Inclusion Criteria

  • pregnant up to 28 weeks gestation,
  • 18 years of age or older,
  • Meets Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for Insomnia disorder as determined by the Sleep Condition Indicator (SCI) or Insomnia Severity Index (ISI) score ≥ 11
  • regular access to a web-enabled computer, tablet, or smart phone.

Exclusion Criteria

  • Probable major depression (Edinburgh Postnatal Depression Scale (EPDS) score ≥ 15),
  • self-reported bipolar disorder,
  • self-reported history of psychosis,
  • active suicidality defined as scoring > 1 on EPDS item 10 or report of a specific suicide plan or recent attempt,
  • shift work employee,
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02805998). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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