N/A
Completed N=90
Stroke and CPAP Outcome Study 2
Sleep Apnea, Obstructive · Stroke · Patient Adherence
Source: ClinicalTrials.gov NCT02809430 ↗
Enrolled (actual)
90
Serious AEs
0.0%
Results posted
Dec 2020
Primary outcomePrimary: 3-month CPAP Adherence — 32 participants adherent to CPAP at 90 days
Summary
Obstructive sleep apnea (OSA) is associated with impaired stroke recovery. Treatment with continuous positive airway pressure (CPAP) may prevent this but is limited by poor adherence. In this study, the investigators enrolled eligible stroke patients undergoing inpatient rehabilitation (IPR) into an intensive CPAP adherence protocol (iCAP) with an aim to increase tolerance and adherence to auto-titrating CPAP (APAP).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY 3-month CPAP Adherence |
32 | — |
| SECONDARY CPAP Tolerance |
52 | — |
| SECONDARY Change in the Cognitive Functional Independence Measure (FIM) Subscore |
8.2; 4.6 | — |
| SECONDARY Change in the Motor Functional Independence Measure (FIM) Subscore |
31.2; 30.2 | — |
| SECONDARY Change in NIH Stroke Scale |
-3.8; -1.6 | — |
Eligibility Criteria
Inclusion Criteria
- Adult patients admitted after acute ischemic or hemorrhagic stroke to one of two inpatient rehabilitation units
Exclusion Criteria
- The investigators will exclude participants if: their stroke was a subarachnoid hemorrhage or due to a secondary cause (vascular malformation, vasculitis, brain tumor, head trauma, or predisposition to bleeding); they have active CPAP use, advanced chronic lung disease requiring supplemental oxygen, heart failure (NYHA class III or IV); or they needed a nasogastric feeding tube.
Data sourced from ClinicalTrials.gov (NCT02809430). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.