N/A N=32 Randomized Double-blind Treatment

Effect of Simultaneous Dual Stimulation on Freezing of Gait in Parkinson's Disease

Parkinson Disease

Bottom Line

View on ClinicalTrials.gov: NCT02850159 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2017

Primary outcome: Primary: Change of Freezing of Gait Questionnaire (FOG-Q) — 12.0; 13.9 score

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: rTMS and tDCS (Device); rTMS (Device)
Age: Adult, Older Adult · 20+ yrs
Sex: All
Sponsor: Samsung Medical Center
Primary completion: Sep 2015

Outcome Measures

Outcome	Result	p-value
PRIMARY Change of Freezing of Gait Questionnaire (FOG-Q)	12.0; 13.9	—

Summary

The purpose of this study is to investigate the effect of dual-mode non-invasive brain stimulation (NIBS) with high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex of the lower leg and anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex compared with rTMS alone in patients with Parkinson's disease (PD) with freezing of gait (FOG).

Eligibility Criteria

Inclusion Criteria

diagnosed as Parkinson's disease (PD) with freezing of gait
walk independently without walking devices

Exclusion Criteria

pre-existing and active major neurological diseases other than PD
a previous history of seizures
implanted metallic objects that would contraindicate rTMS

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02850159). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.