N/A
Completed N=99
Breathing Interventions for Relaxation: Dosing Through Extended Exhale
Healthy Adults · Stress
Source: ClinicalTrials.gov NCT02870868 ↗
Enrolled (actual)
99
Serious AEs
0.0%
Results posted
May 2024
Primary outcomePrimary: Magnitude of Change in High Frequency Heart Rate Variability — 399; 421 milliseconds^2
Summary
Breathing exercises are categorized as a mind-body practice. One in ten adults in the U.S. use breathing exercises for health purposes. The aim of this project is to examine if different slow breathing has different physiological and psychological effects.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Magnitude of Change in High Frequency Heart Rate Variability |
381; 487 | — |
| PRIMARY Magnitude of Change in High Frequency Heart Rate Variability |
381; 487 | — |
| PRIMARY Magnitude of Change in High Frequency Heart Rate Variability |
381; 487 | — |
| PRIMARY Magnitude of Change in PROMIS Anxiety Scale |
52.0; 51.2 | — |
| PRIMARY Magnitude of Change in PROMIS Anxiety Scale |
52.0; 51.2 | — |
| PRIMARY Magnitude of Change in PROMIS Anxiety Scale |
52.0; 51.2 | — |
Eligibility Criteria
Inclusion Criteria
- Age 30 to 60 years
- English speaking
Exclusion Criteria
- Hypertension
- Heart disease: history of coronary artery disease, myocardial infarction, significant valvular disease, or congestive heart failure
- Diabetes
- Renal disease
- Anxiety disorder
- Depression
- Other psychiatric conditions including schizophrenia or bipolar disorder
- Attention-deficit-disorder or Attention-deficit-hyperactivity disorder
- Musculoskeletal condition limiting capacity to perform simple movements such as chronic lower back pain or neck pain
- Pulmonary disorder (asthma, chronic obstructive lung disease, obstructive sleep apnea)
- Smoker
- Currently taking blood pressure medications, oral diabetic medication or insulin
- Current participation in a mind-body practice/program
- Current cancer other than non- melanoma skin cancer
- Regular swimmer
- Plays wind or brass musical instruments
After two weeks during screening period unable to:
- Breathe 8 or less a minute
- Breathe 3 or less breaths a minute
- Practiced less than 3 times a week
Data sourced from ClinicalTrials.gov (NCT02870868). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.