N/A
N=22
Medical Marijuana and Its Effects on Motor Function in People With Multiple Sclerosis
Multiple Sclerosis
Bottom Line
View on ClinicalTrials.gov: NCT02898974 ↗Enrolled (actual)
22
Serious AEs
0.0%
Results posted
Feb 2020
Primary outcome: Primary: Fatigue — 21; 24 % decline
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Medical Marijuana (Behavioral)
- Age
- Adult · 30+ yrs
- Sex
- All
- Sponsor
- Colorado State University
- Primary completion
- Oct 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Fatigue |
21; 24 | — |
| PRIMARY Muscle Strength |
28.7; 33.6 | — |
| PRIMARY Postural Stability |
9.2; 11.5 | — |
Summary
Medical marijuana is commonly prescribed people with Multiple Sclerosis (MS) for symptom, e.g. spasticity and pain, management. Unfortunately not much is known about its effects outside the treatment for these 2 symptoms. Several previous studies have suggested people with MS using medical marijuana have lower levels of physical disability and improved walking abilities. A major limitation of these previous studies is that the investigators used subjective measures of motor function. In this proposed observational case-control study the investigators plan to objectively measure multiple domains of motor function, such as: fatigue, strength, and walking ability. No marijuana will be brought on to campus or given to participants.
Eligibility Criteria
Inclusion Criteria
- Medically diagnosed with MS,
- 30-60 years of age,
- Moderate disability (Patient Determined Disease Steps score 2-6).
Exclusion Criteria
- Relapse with the last 60 days,
- High risk for cardiovascular disease (American College of Sports Medicine risk classification),
- Changes in disease modifying medications within the last 45 days,
- Concurrent neurological/neuromuscular disease,
- Hospitalization within the last 90 days,
- Inability to understand/sign informed consent.
Data sourced from ClinicalTrials.gov (NCT02898974). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.