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N/A N=280 Randomized Quadruple-blind Prevention

Individualized Analgesia After Adenotonsillectomy

Analgesia

Enrolled (actual)
280
Serious AEs
0.0%
Results posted
Aug 2017
Primary outcome: Primary: The Percentage of Patients Requiring at Least One Medical Intervention for Respiratory Events — 16; 29 Participants — p=<0.05

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Individualized opioid analgesia (Drug); conventional opioid analgesia (Device)
Age
Pediatric · 3+ yrs
Sex
All
Sponsor
Children's Hospital of Fudan University
Primary completion
Feb 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
The Percentage of Patients Requiring at Least One Medical Intervention for Respiratory Events
16; 29 <0.05 sig
SECONDARY
The Median Survival Time for CHEOPS Score > 6.
20; 30

Summary

A high incidence of respiratory morbidity after adenotonsillectomy is reported in children with obstructive sleep apnea syndrome (OSAS). So we designed a prospective, double-blind, randomized controlled study to determine the effects of individualized opioid analgesia compared with conventional opioid analgesia on respiratory morbidity after adenotonsillectomy in Children with OSAS.

Eligibility Criteria

Inclusion Criteria

  • children with obstructive sleep apnea syndrome undergoing elective T&A, ASA physical status I-II

Exclusion Criteria

  • developmental delay cardiac and craniofacial abnormalities ASA classification III or more body mass index more than the 95th percentile for age
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02990910). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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