Phase 3 N=105 Analgesic Effect of Peripheral Dexmedetomidine
Third Molar Extraction
Primary: Pain Score at Rest — 165.5; 218.2; 233.8 score on a scale×hr
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=76 Local Anesthesia and Pain Perception During an Amniocentesis
Pregnancy
Primary: Intensity of Perceived Maternal Pain as Measured by the Visual Analogue Scale (VAS) — 9.5; 18.4 units on a scale
Phase 3 N=17 Neuroimaging Study of Dexmedetomidine-Induced Analgesia
Analgesia · Anesthesia
Primary: CSF Flow Measured in Hz — -15 Hz
Phase 2 N=250 Analgesic Effect of IV Acetaminophen in Tonsillectomies
Adenotonsillitis · Tonsillitis
Primary: FLACC Pain Score Greater Than or Equal to 4 — 58; 69 Participants
N/A N=94 Opioid Sparing Potential of Light-Induced Analgesia
Pain
Primary: Change in Pain Level — 1.15; -0.04; 1.07 score on a scale
N/A N=110 Analgesia in Laparoscopic Cholecystectomy
Pain, Postoperative · Chronic Postoperative Pain
Primary: VAS Score Changes ( Cough) During 24 h Postoperatively — 32; 31 mm
N/A N=200 Non-invasive Assessment of Immediate Postoperative Analgesia Using Analgesia/Nociception Index (ANI)
Postoperative Pain
Primary: Analgesia/Nociception Index (ANI) — 73; 49 units on a scale
Phase 2 N=38 Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Fentanyl
Healthy
Primary: Cumulative Stress Index — 647; 676 mmHg x minutes
Phase 2 N=46 Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Sufentanil
Healthy
Primary: Tolerance to Simulated Hemorrhage — 599; 651 min*mmHg
Phase 4 N=100 A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery
Opioid Use
Primary: Amount of Pain Experienced — 28; 35 Score on a scale
N/A N=20 Effects of IV Administration of Ketamine on the Analgesia Nociception Index (ANI) Measured With the PhysioDoloris
Monitoring, Intraoperative
Primary: Mean ANI Changes After Intubation — 2.11 index
Phase 4 N=80 Analgesia After Total Shoulder Arthroplasty
Total Shoulder Arthroplasty
Primary: Numeric Rating Scale (NRS) Pain Score With Movement — 4.5; 3.4; 4.2; 4.9 units on a scale
N/A N=54 Analgesic Efficacy After Umbilical Hernia Repair in Children
Umbilical Hernia
Primary: The Amount of Intravenous and Oral Opioids Used by Patients Who Receive a Rectus Sheath Nerve Block and Those Who Receive Local Infiltration of the Surgical Site for…
N/A N=100 Vibration Analgesia in Propofol Infusion During Anesthesia Induction
Pain, Acute
Primary: Level of Pain as Observed by Two Independent Observers Following Propofol Injection, With or Without a Vibration Analgesia Adjunct — 3.1; 1.4 units on a scale
N/A N=84 Decreasing Postoperative Pain Following Endometrial Ablation
Postoperative Pain
Primary: Postoperative Pain Score — 2.71; 1.44; 3.37; 2.81 units on a scale
N/A N=280 Individualized Analgesia After Adenotonsillectomy
Analgesia
Primary: The Percentage of Patients Requiring at Least One Medical Intervention for Respiratory Events — 16; 29 Participants — p=<0.05
Phase 4 N=50 Analgetic and Anxiolytic Effect of Preoperative Pregabalin
Intervertebral Disk Displacement · Disk Prolapse
Primary: Mean VAS Pain (Visual Analogue Scale)at Rest (0-100 mm) — 11.7; 22.5 Units on a scale
N/A N=122 Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery
Postoperative Pain · Wisdom Tooth
Primary: Number of Patients Needing Rescue Medication — 32; 29 Participants
Phase 1 N=30 Neural Correlates of Lidocaine Analgesia
Anesthesia · Pain
Primary: Brain Activation to Painful Stimulation Difference: Drug-free Condition Minus Lidocaine Condition — 3.6 Z-score — p=0.004
N/A N=90 Analgesia After Total Hip Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia (PCA)
Osteoarthritis
Primary: Time Until Patient is Ready for Discharge — 2.4; 2.3 days
Phase 4 N=67 Infiltration Analgesia After Caesarean Section
Pain, Postoperative · Caesarean Section
Primary: The Demand of Rescue Analgesics (Oxycodone) — 47.5; 57.8 mg — p=0.10
Phase 4 N=30 Peripheral Nerve Blocks for Above-the-knee Amputations
Peripheral Vascular Diseases · Hyperglycaemia (Diabetic) · Hypertension
Primary: Peripheral Nerve Block Success as a Primary Anesthetic — 1 Participants
N/A N=11 Evaluation of Procedural Analgesia for Liposonix Treatment
Body Contouring
Primary: Pain Score for Overall Treatment — 6.3 units on a scale
N/A N=180 Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients
Pain · Anesthesia
Primary: Mechanical Hyperalgesia Threshold on the Dominant Inner Forearm — 60.57; 78.29; 68.50; 79.7 g
N/A N=46 Reducing Post-Op Pain After Sacrospinous Ligament Colpopexy
Pain
Primary: Postoperative Gluteal Pain — 3.6; 4.0; 2.0; 2.0 units on a scale — p=0.83
Phase 2 N=44 Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Morphine
Healthy
Primary: Tolerance to Simulated Hemorrhage — 385; 692 CSI: Cumulative Stress Index
N/A N=150 Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia
Pain · Anesthesia
Primary: Mechanical Hyperalgesia Threshold on the Dominant Inner Forearm — 61.5; 88.2; 73.0; 67.2 g
N/A N=120 Postoperatory Analgesia After Total Knee Arthroplasty
PAIN
Primary: Postoperatory Analgesia After Total Knee Arthroplasty Comparing Femoral and Sciatic-femoral Block — 2; 2.8; 1.5 units on a scale
Phase 4 N=62 Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors
Pituitary Tumor · Pain
Primary: Comparison of Mean Pain Scores Between Two Arms (Measured Every 4 Hours Over 48 Hour) — 1.7; 2.8 0-10 units on a scale
Phase 4 N=258 CATHETER ANALGESIA TRIAL Phenazopyrdine vs. Placebo: a Randomized Controlled Trial
Catheter-related Bladder Discomfort
Primary: Reduction of Catheter-associated Discomfort During the Post-operative Period in the Gynecologic Patient Using Mean Visual Analogue Scale (VAS) Measurments — 0.95; 0.97…