N/A Completed N=21 Randomized Single-blind Basic Science

Effects of Short-term Curcumin and Multi-polyphenol Supplementation on the Anti-inflammatory Properties of HDL

Inflammation · Atherosclerosis · Cardiovascular Disease

Source: ClinicalTrials.gov NCT02998918 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2023

Primary outcomePrimary: Inflammation Change: HDL Plasma — NA; NA AU

Summary

Polyphenol supplements, including curcumin and resveratrol, are known to decrease inflammation, but previous polyphenol supplements were poorly absorbed and thus their effects were reduced. A new phytosome formulation coats the supplements and allows them to be better absorbed. The purpose of this study is to examine the acute (1-hr) and short-term (1-week) effects of two different phytosome-formulated polyphenol supplements on inflammation. The two supplements that will be used are: 1) PolyResveratrol and 2) Curcumin.

Outcome Measures

Outcome	Result	p-value
PRIMARY Inflammation Change: HDL Plasma	NA; NA	—

Eligibility Criteria

Inclusion Criteria

General good health
Between 18 and 60 years old
Non-smoker
Not taking any medications or dietary supplements

Exclusion Criteria

Taking prescription anti-inflammatory drugs or supplements/drugs that may affect inflammation

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02998918). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.