N/A
N=187
GER Poses a Potential Risk for Late Complications of BPD
Gastroesophageal Reflux · Bronchopulmonary Dysplasia
Bottom Line
View on ClinicalTrials.gov: NCT03014453 ↗Enrolled (actual)
187
Serious AEs
55.2%
Results posted
Mar 2020
Primary outcome: Primary: the Late Complications of BPD Infants — 57; 45; 30; 4 Participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Pediatric
- Sex
- All
- Sponsor
- Shengjing Hospital
- Primary completion
- Jun 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY the Late Complications of BPD Infants |
57; 45; 30; 4; 1; 31 | — |
Summary
Bronchopulmonary dysplasia (BPD) is a common condition in the low birth weight infants. Although most of the BPD symptoms improved after a regular treatment in infancy, there are still a few late complications left such as the frequent respiratory symptoms, a slower weight gain and even sudden death. These late complications have made so much trouble to the healthcare of BPD infants. How to find the risk factors and to reduce the prevalence of these late symptoms becomes necessary. In this study, a cohort of BPD infants was observed with the late complications obtained by a monthly followed up for 18 months after discharge, the prevalence and risk factors of the late complications of BPD were analyzed by logistic regression. As one of the risk factors, GER was verified whether to play a critical role in these late complications.
Eligibility Criteria
Inclusion Criteria
- the extremely premature infants with bronchopulmonary dysplasia
Exclusion Criteria
- other congenital malformations such as gastrointestinal and or neurogenic disease
Data sourced from ClinicalTrials.gov (NCT03014453). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.