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Home › Conditions › Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia

Part of EVALI

5 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Bronchopulmonary Dysplasia

24 trials tracked for Bronchopulmonary Dysplasia: 7 in phase 3 or 4 and 3 with published results. The most-cited published study has 108 citations.

24Trials tracked
7Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 1 Phase 3 6 Phase 2 7 Phase 1 2 Other / NA 8
  1. Phase 3 Hydrocortisone for BPD Completed · 108 cited
  2. Phase 3 Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia Completed · 83 cited
  3. Phase 3 Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide Completed · 25 cited
  4. Phase 4 Preterm Infant Inhaled Albuterol Dosing Completed
  5. Phase 3 Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants Completed
  6. Phase 3 Surfactant Positive Airway Pressure and Pulse Oximetry Trial Completed
Show 18 more trials
  1. Phase 3 Palivizumab for Prevention of Severe Respiratory Syncytial Virus Infection in Russian Children Completed
  2. Phase 2 Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia (BPD) Completed
  3. Phase 2 Safety of Sildenafil in Premature Infants Completed
  4. Phase 2 Randomized Trial of Hydrocortisone in Very Preterm High-Risk Infants Completed
  5. Phase 2 Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respiratory Distress Syndrome Completed
  6. Phase 2 Examining the Use of Non-Invasive Inhaled Nitric Oxide to Reduce Chronic Lung Disease in Premature Newborns Completed
  7. Phase 2 Trial II of Lung Protection With Azithromycin in the Preterm Infant Completed
  8. Phase 2 Antibiotic "Dysbiosis" in Preterm Infants Completed
  9. Phase 1 Inhaled Tobramycin in BPD Completed
  10. Phase 1 Enteral L Citrulline Supplementation in Preterm Infants - Safety, Efficacy and Dosing Completed
  11. N/A Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator Completed
  12. N/A Analysis of BPD in Premature Infants With Typical Imaging Changes Completed
  13. N/A BPD Saturation TARgeting Completed
  14. N/A Comparison of Classification Standards of Bronchopulmonary Dysplasia (BPD) in Premature Infants Completed
  15. N/A GER Poses a Potential Risk for Late Complications of BPD Completed
  16. N/A Relationship Between EIT and Respiratory Status in Very Preterm Infants Completed
  17. N/A Effective Approaches & Strategies to Ease Off Nasal CPAP In Preterm Infants Completed
  18. N/A Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants Completed

Showing the 24 most-cited and recently-updated of 24 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
High-Dose Vitamin D and Low-Dose Vitamin A May Reduce Bronchopulmonary Dysplasia in Preterm Infants
Pediatrics Meta-analysis
High-Dose Vitamin D and Low-Dose Vitamin A May Reduce Bronchopulmonary Dysplasia in Preterm Infants High-Dose Vitamin D May Reduce BPD in Preterm Infants
A network meta-analysis of 4357 preterm infants found that high-dose vitamin D (≥800 IU/d) most notably reduced bronchopulmonary dysplasia i…
A large analysis of preterm infants found that high-dose vitamin D (≥800 IU/day) may lower the risk of bronchopulmonary dysplasia, while low…
NEJM Jun 4, 2026
LSTM analysis of infant tidal breathing detects bronchopulmonary dysplasia with 97% accuracy
Pulmonology & Critical Care Cohort
LSTM analysis of infant tidal breathing detects bronchopulmonary dysplasia with 97% accuracy New AI tool reads baby breath to spot lung disease early
This cohort study of 329 infants and 135 school-age children used recurrent neural networks to analyze tidal breathing flow time series.
A new computer model can read a baby's simple breathing pattern to find lung disease before it becomes serious.
medRxiv Apr 29, 2026
Narrative review examines high-risk factors and major nursing interventions for bronchopulmonary dysplasia in premature infants
Pediatrics Sys. Review
Narrative review examines high-risk factors and major nursing interventions for bronchopulmonary dysplasia in premature infants Nursing care and risk factors for lung disease in premature babies
This narrative review addresses high-risk factors for bronchopulmonary dysplasia and major nursing interventions in premature infants.
This review looks at how nursing interventions and high-risk factors affect premature infants with bronchopulmonary dysplasia, offering insi…
Frontiers Apr 24, 2026
Closed-loop oxygen control shortens ventilation and oxygen duration in preterm infants in RCT
Pediatrics RCT
Closed-loop oxygen control shortens ventilation and oxygen duration in preterm infants in RCT New Technology Helps Preterm Babies Spend Less Time on Ventilators
This randomized controlled trial in 69 preterm infants compared closed-loop automated oxygen control to manual control.
A smart oxygen system helped preterm babies breathe on their own sooner, cutting ventilator time and reducing lung disease risk.
Apr 19, 2026
Lung ultrasound scores higher in children with moderate-to-severe BPD; abnormal scores may aid readmission risk assessment
Pediatrics Cohort
Lung ultrasound scores higher in children with moderate-to-severe BPD; abnormal scores may aid readmission risk assessment Lung ultrasound scores differ in children with severe bronchopulmonary dysplasia
A cross-sectional cohort study of 125 children aged 0–24 months found higher lung ultrasound scores in those with Grade 2 and 3 bronchopulmo…
A single lung ultrasound can spot breathing trouble risks in children with severe lung disease, though normal scans do not rule out the cond…
Frontiers Apr 5, 2026

Questions about Bronchopulmonary Dysplasia

What nursing interventions are recommended for premature infants at high risk for bronchopulmonary dysplasia?

Nursing care for premature infants at risk of bronchopulmonary dysplasia focuses on precise oxygen control, adequate staffing, and early detection using breathing pattern analysis.

Full answer →
Can breathing patterns detected by AI help diagnose bronchopulmonary dysplasia in infants?

Yes, AI analysis of breathing patterns can help diagnose bronchopulmonary dysplasia in infants, with one study showing 97% accuracy using LSTM networks on tidal breathing data.

Full answer →