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N/A N=82 Randomized Single-blind Treatment

Efficacy Study of FES Controlled by Electromyographic Signal for the Treatment of Upper Limb in Post-stroke Patients

Stroke

Enrolled (actual)
82
Serious AEs
0.0%
Results posted
Sep 2018
Primary outcome: Primary: Change Score of ARAT Scale Between Two Time Points: Post-treatment vs Pre-treatment — 6.6; 5.0 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
MeCFES-assisted task-oriented upper limb rehabilitation (Device); Usual Care task-oriented upper limb rehabilitation (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Fondazione Don Carlo Gnocchi Onlus
Primary completion
Nov 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Change Score of ARAT Scale Between Two Time Points: Post-treatment vs Pre-treatment
6.6; 5.0
PRIMARY
Change Score of FMA-UE Scale Between Two Time Points: Post-treatment vs Pre-treatment
7.8; 4.5
SECONDARY
Change Score of IPPA Between Two Time Points: Post-treatment vs Pre-treatment
-2.8; -3.2
SECONDARY
Change Score of DASH Between Two Time Points: Post-treatment vs Pre-treatment
-4.8; -7.4
SECONDARY
Change Score of VAS for Perceived Pain Between Two Time Points: Post-treatment vs Pre-treatment
0; 0

Summary

Goal of the present study is to evaluate the efficacy of Myoelectrically-controlled Functional Electrical Stimulation (MeCFES) for the rehabilitation of upper limb in post-stroke patients. MeCFES-assisted rehabilitation will be compared with usual care rehabilitation of upper limb. It is hypothesized that that applying MeCFES in rehabilitation to assist normal arm movements during rehabilitation of the upper limb in persons with stroke will improve the movement quality and success and thus induce recovery at the body functions level (impairment) and the activity level (disability) of the International Classification of Function (ICF) superior to that induced by usual care rehabilitation.

Eligibility Criteria

Inclusion Criteria

  • Hemiplegia/hemiparesis due to a first ischemic or haemorrhagic stroke
  • at least 1 month post-stroke
  • willingness to participate the project
  • minimum voluntary muscle activation of shoulder flexors (>1 Manual Muscle Test)
  • passive Range of Motion (ROM) of the shoulder and elbow of more than 90°

Exclusion Criteria

  • epilepsy
  • severe spasticity at upper limb (>= 3 Ashworth scale)
  • implanted electronic device
  • respiratory insufficiency
  • pregnancy
  • peripheral neuropathies
  • cutaneous ulcers at the stimulation zone
  • other use of FES on the upper limb
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03019744). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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