Phase 4
Completed N=71
Oral Ketorolac for Pain Relief During IUD Insertion
Source: ClinicalTrials.gov NCT03031795 ↗Enrolled (actual)
71
Serious AEs
0.0%
Results posted
Sep 2018
Primary outcomePrimary: Pain Before, During and After IUD Placement — 4.1; 4.5; 0.4; 0.7 units on a scale — p=< 0.05
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
Ketorolac is a non-steroidal anti-inflammatory drug (NSAID), similar to ibuprofen but it is used to treat more severe pain. Ketorolac (Trade name: Toradol) is typically used after surgical procedures. When taken orally, it should not cause sedation. The purpose of this study is to determine if oral ketorolac is effective at reducing pain during IUD placement versus a placebo tablet.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Before, During and After IUD Placement |
4.1; 4.5; 0.4; 0.7; 2.7; 3.2 | < 0.05 sig |
Eligibility Criteria
Inclusion Criteria
- non-pregnant
- English speaking women
- 18 years of age or older desiring an IUD for contraception
Exclusion Criteria
- enrollment in another study
- pre-medication with any type of analgesic medication
- contraindication to an IUD
- weight under 50 kg
- allergy to non-steroidal anti-inflammatory medications
- past medical history of liver disease, renal disease, peptic ulcer disease or recent gastrointestinal bleed,
- daily narcotic pain use
- positive cultures for gonorrhea or chlamydia.
Data sourced from ClinicalTrials.gov (NCT03031795). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.