N/A
Completed N=8
Low Intensity Blood Flow Restriction Training Study
Muscle Mass
Source: ClinicalTrials.gov NCT03055260 ↗
Enrolled (actual)
8
Serious AEs
0.0%
Results posted
Feb 2020
Primary outcomePrimary: One Repetition Maximum — 302.9 pounds
Summary
The particpant will complete baseline testing by measuring subjects' quadriceps muscle thickness (cm) via ultrasound technology, as well as have them complete a one repetition maximum (1RM) test on the leg press machine and an isometric knee extension using a dynamometer - strength measures will be calculated for both right and left legs. After baseline testing, subjects will complete 6 weeks of the testing protocol that will consist of leg press exercises at 30% of their 1RM. Subjects will be randomized to either wear a cuff that partially restricts blood flow to the limb (Study Group), or to wear a cuff that does not restrict blood flow (Control Group). Exercises will be completed 2x/week and will take approximately 10 total minutes (5 for warm up, 5 for testing protocol) per session. After 6 weeks, muscle thickness, leg press 1RM, and quadriceps extension strength will be re-tested and compared to the initial measurements.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY One Repetition Maximum |
302.9 | — |
| SECONDARY Quadriceps Muscle Thickness |
45 | — |
Eligibility Criteria
Inclusion Criteria
- Age 18-49
Exclusion Criteria
- Pregnant
- Hypertensive
- Recent back or lower extremity injury
- History of blood clotting
- Varicose veins
- Adults lacking the capacity to consent for themselves
Data sourced from ClinicalTrials.gov (NCT03055260). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.