N/A N=40 Muscle Mass During Space Exploration
Muscle Loss
Primary: Lean Leg Mass — -1.2; -0.9 g
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=37 Exercise to Prevent Muscle Mass and Functional Loss in Elderly Dialysis Patients
Chronic Kidney Disease
Primary: Maximal Oxygen Uptake — 14.5; 15.1 ml/kg/min
N/A N=44 Mechanisms Underlying Local and Systemic Effects of Massage
Muscle Atrophy
Primary: Percent Change in Myofiber Cross Sectional Area (CSA). — -15.1; -13.4 percent change from baseline
Phase 4 N=34 Effect of Vitamin D Supplementation on Muscle Mass and Function
Obesity · Insulin Resistance · Inflammation
Primary: Muscle Function — 1.14; 1.50 kilograms
N/A N=16 Effect of Exercise on the Human Skeletal Muscle Phosphoproteome
Skeletal Muscle Protein Synthesis
Primary: Change in Acute Muscle Protein Synthesis — 143; 123 percent change
N/A N=21 Time Course Adaptations Using Deuterated Creatine (D3Cr) Method
Sarcopenia
Primary: Muscle Mass — 3.47; 1.19 Kg — p=0.03
N/A N=40 Assessment of Body Composition and Physical Function
Body Composition · Physical Function
Primary: Fat Mass — 44.71 Kg
N/A N=141 Impact of Protein and Alkali Supplementation on Skeletal Muscle in Older Adults
Age-Related Sarcopenia · Muscle Loss
Primary: Double Leg Press Peak Power at 70% — 260.3; 255.6; 251.1; 264.8 Watts
N/A N=80 Effect of Whey Protein Supplementation and Resistance Exercise on Muscle Parameters in Older Adults
Mobility Limitation
Primary: 1 Repetition Maximum Muscle Strength 1-RM (N) Double Leg Press — 1223; 1256; 1483; 1465 N
N/A N=22 Regulation of Muscle Protein Phenotype in Humans With Obesity
Obesity
Primary: Whole-Muscle Protein Synthesis — 0.004; 0.015 %/hr
N/A N=16 Effect of an EAA/Whey Composition on Protein Metabolism
Sarcopenia
Primary: Protein Anabolism — 3.56; 11.8; 3.02 grams — p=<0.05
N/A N=16 Functional Change With MMS
Muscle Weakness
Primary: Change in Body Satisfaction Questionnaire From Baseline to 1-month Post-Treatment Follow-up Visit — 8.6 units on a scale
N/A N=14 Muscle Capillarization and Sarcopenia
Sarcopenia
Primary: Skeletal Muscle Capillarization — 0.4; 0.2 capillaries per muscle fiber — p=0.27
Phase 1 N=32 Effect of a Ghrelin Receptor Agonist on Muscle and Bone
Sarcopenia · Osteopenia
Primary: Total Body Muscle Mass — 21.8; 20.8; 22.2; 20.8 kg units on a scale
N/A N=30 Nutritional Biomarkers of Sarcopenia
Sarcopenia
Primary: Resting and Maximum Plasma Leucine Concentration — 659; 755; 721; 95 micromoles per liter
Phase 1 N=62 Muscle Perfusion and Protein Metabolism in Elderly
Aging
Primary: Mixed Muscle Fractional Synthesis Rate (FSR) — 0.061; 0.070; 0.066; 0.070 Fractional Synthesis Rate (pecent/hour)
N/A N=29 Role of the Gut Microbiome on Lean Mass and Physical Function in Older Adults
Sarcopenia
Primary: Percentage of Whole Body Lean Mass (%WBLM) — 67.3; 61.9 % of whole body mass
N/A N=12 Impact of Muscle Temperature on Muscle Growth and Breakdown: Cooling During Resistance Training
Exercise Training
Primary: RT-qPCR for Forkhead Box O3 (FOXO3a) — 1.24; 1.30 fold change — p=.609
N/A N=20 Preventing the Loss of Muscle and Function in Hospitalized Older Adults
Muscular Atrophy
Primary: The Percent Change in Bilateral Thigh Lean Mass Density (Grams) as Measured by DEXA Scan Will be Compared Between Baseline and After 5-days of Bed Rest — -3.845; -0.249…
Phase 3 N=50 Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
Muscle Weakness
Primary: Rectus Femoris Cross Sectional Height — 17.5; 17.6 cm
N/A N=61 Muscle Growth Following a Resistance Training Program in Men and Women Consuming Protein Supplements
Skeletal Muscle Growth
Primary: Lean Body Mass Change — 1.5; 1.3 kilogram — p=<0.05
N/A N=44 Immune Function and Muscle Adaptations to Resistance Exercise in Older Adults
Sarcopenia · Aging · Immune Function
Primary: Change in Plasma Concentration of Antibodies to Pertussis Antigen (1 Week Post-vaccine) — 63.1; 63.2 units per ml — p=>0.05
N/A N=37 Forearm Immobilization, Metabolic Health, and Muscle Loss
Healthy
Primary: Percent Change in Forearm Glucose Uptake — -73; 127; -95 Percent change in clamp FGU with immob
Phase 2 N=120 Metformin and Muscle in Insulin-resistant Older Veterans
Prediabetes
Primary: Change in Total Lean Mass From Baseline — 322.8; 697.6; 392.4; 548.0 grams lean mass — p=0.45
N/A N=38 Training Induced Muscle Exosome Release
Metabolism
Primary: miR-1 Abundance — 226; 110; 286 percent change
Phase 2 N=159 Study of GTx-024 on Muscle Wasting (Cachexia) Cancer.
Cachexia
Primary: The Efficacy of GTx-024 on Total Body Lean Mass. — 1.55; 0.98; 0.02 kg
Phase 2 N=170 A Study of the Safety and Efficacy of MK-0773 in Women With Sarcopenia (Loss of Muscle Mass)(MK-0773-005)
Sarcopenia
Primary: Change From Baseline in Participant Lean Body Mass — 1.26; 0.29 kg
N/A N=150 Generation of Prediction Equations for BIA of the Elderly
Healthy Elderly
Primary: Total Body Water — 1.85 liter
N/A N=68 Blood Flow, Muscle Regeneration and Sarcopenia
Sarcopenia
Primary: Muscle Satellite Cells — 3.2; 3.2; 4.0; 3.8 Number of Pax7+ cells/muscle fiber
N/A N=13 (KIWI) Speeding up a Slow Protein for Muscle Mass With Hay Kiwifruit
Metabolism · Protein
Primary: Whole Body Net Balance Measured by Gas Chromatography-Mass Spectrometry (GC-MS) — 14.58; 14.55 g protein per 300 mins