Phase 4
Completed N=60
Comparison of Obturator Nerve Blockade and Neuromuscular Blockade
Source: ClinicalTrials.gov NCT03063255 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Mar 2021
Primary outcomePrimary: Number of Patients With Incidence of Intraoperative Adductor Spasm — 1; 5 Participants
◆ Published Evidence
Emerging
8citations · ~2 / year
Obturator Nerve Blockade vs. Neuromuscular Blockade for the Prevention of Adductor Spasm in Patients Undergoing Transurethral Resection of Bladder Tumors: A Randomized Controlled Trial.
Summary
Patients diagnosed with posterolateral bladder tumors will be invited to participate in the study. Subjects will be randomized to receive an ultrasound-guided obturator block or a neuromuscular blocking agent after the induction of general anesthesia in an attempt to block the obturator reflex during surgery.
Linked Publications
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Obturator Nerve Blockade vs. Neuromuscular Blockade for the Prevention of Adductor Spasm in Patients Undergoing Transurethral Resection of Bladder Tumors: A Randomized Controlled Trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Patients With Incidence of Intraoperative Adductor Spasm |
1; 5 | — |
| SECONDARY Number Patients With Increased Risk of Falling |
28; 29 | — |
| SECONDARY Number of Patients With Incidence of Leg Weakness |
27; 22 | — |
Eligibility Criteria
Inclusion Criteria
- Patients ≥ 18 years of age
- Planned TURBT for unilateral or bilateral posterolateral bladder tumors
- Ability to understand and provide informed consent
Exclusion Criteria
- Patient refusal or inability to provide informed consent
- True allergy, not sensitivity, to local anesthetics
- True allergy, not sensitivity, Propofol
- True allergy, not sensitivity, general anesthetic agents
- Pregnancy
- Severe hepatic impairment
- Evidence of infection at or near the proposed needle insertion site
- Any sensorimotor deficit of the lower extremity, whether acute or chronic
- Inability to walk without assistance
- Lower extremity joint replacement surgery in the preceding six months
Data sourced from ClinicalTrials.gov (NCT03063255) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.