Phase 4
Completed N=242
Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Tract Infection
Source: ClinicalTrials.gov NCT03099863 ↗Enrolled (actual)
242
Serious AEs
0.0%
Results posted
Dec 2021
Primary outcomePrimary: Urinary Tract Infection — 11; 12 UTI
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
Postoperative urinary tract infections (UTIs) affect 20-30% of patients undergoing elective gynecologic surgery and have a significant socioeconomic impact and cost. Preoperative antibiotics, sterile operating techniques, postoperative antibiotic and non-antibiotic medical therapies have been utilized to attempt to decrease this rate with little improvement. Utilization of an intraoperative antibiotic cystoscopic irrigant may decrease postoperative UTIs. The investigators have designed a prospective randomized controlled study to evaluate the effectiveness of an antibiotic cystoscopic fluid in preventing postoperative urinary tract infections in women undergoing elective pelvic floor surgery with cystoscopy.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Urinary Tract Infection |
11; 12 | — |
Eligibility Criteria
Inclusion Criteria
- Adult women at least 18 years of age
- Elective Female Pelvic Medicine and Reconstructive Surgery or Gynecologic Minimally Invasive surgeries including hysterectomy, suburethral sling, and pelvic organ prolapse repair that require cystoscopy.
Exclusion Criteria
- Surgeries that include: intradetrusor Botox, vaginal mesh excision, and fistula repair
- Pregnancy
- History of nephrolithiasis
- Allergy to study medications
- Congenital urogenital anomaly
- Neurogenic bladder
Data sourced from ClinicalTrials.gov (NCT03099863). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.