Meta-analysis finds high fluoroquinolone resistance in E. coli causing UTIs globally
1 in 3 UTI E. coli cases now resist common antibiotics
This meta-analysis of 36 studies reports a pooled fluoroquinolone resistance prevalence of 31.09% in E. coli from UTIs. Resistance varied by…
A global review finds that nearly a third of E. coli from UTIs are resistant to key fluoroquinolone antibiotics, making infections harder to…
Cefepime-nacubactam and aztreonam-nacubactam non-inferior for complicated UTI and pyelonephritis
New antibiotics show promise for complicated urinary tract infections
This phase 3 randomised double-blind study in adults with complicated urinary tract infection or acute uncomplicated pyelonephritis found ce…
A large trial found new antibiotic combinations worked better than standard care for certain urinary infections in adults.
Critical narrative review discusses barriers to implementing urinary tract infection diagnostics in clinical practice
New tests for urinary tract infections could help fight antibiotic resistance
This critical narrative review addresses the challenges of integrating diagnostic innovations for urinary tract infections into frontline he…
A review finds that rapid diagnostic tests for UTIs could reduce unnecessary antibiotic use, but cost and policy barriers slow their adoptio…
Nitrofurantoin outperforms single-dose fosfomycin for uncomplicated UTIs in Spanish primary care
Nitrofurantoin beats single-dose fosfomycin for common bladder infections in women
This Phase 4 randomized clinical trial evaluated four antibiotic regimens in women with uncomplicated urinary tract infections in Spanish pr…
New research shows nitrofurantoin works better than single-dose fosfomycin for curing common bladder infections in women.
Review of ESBL-producing E. coli epidemiology and fluoroquinolone resistance in Mexican community isolates
UTIs Are Getting Harder to Treat — Here’s Why
This retrospective cross-sectional study reviews community-acquired E.
This could change how doctors choose antibiotics for UTIs.
Retrospective study finds low resistance to key antibiotics in TB patients with UTIs
When TB Treatment Hits a Wall: The Hidden Bladder Problem
A retrospective cohort study of 1,151 bacterial strains from tuberculosis patients with urinary tract infections at a single hospital found …
Tuberculosis patients with urinary infections face drug-resistant bacteria, but a five-year hospital review reveals which antibiotics still …
Meta-analysis finds 30.5% breakthrough UTI rate in children with VUR on antibiotic prophylaxis
A Scorecard to Spot Kids at Highest Risk of Kidney Infections
A meta-analysis of 24 cohort studies (n=3,264) in children with vesicoureteral reflux on continuous antibiotic prophylaxis found a pooled br…
A new eight-clue scorecard helps doctors spot which children on daily antibiotics are most likely to still get a kidney infection.
Dipstick urinalysis shows high specificity but low sensitivity for UTI in febrile infants under 12 months
A Simple Strip That Spots UTIs in Babies
A retrospective single-center cohort study of febrile infants aged 0–12 months with suspected UTI evaluated dipstick urinalysis against urin…
A simple bedside urine test can help doctors spot kidney infections in babies under one year, with specificity up to 99 percent when nitrite…
FDA Approves Cefepime for Injection and Dextrose Injection (cefepime) for Moderate to Severe Pneumonia and Other Infections
The FDA approved a new ready-to-use version of an antibiotic called cefepime for serious infections
The FDA approved cefepime in a dextrose injection formulation for intravenous treatment of moderate to severe pneumonia, febrile neutropenia…
The FDA approved a ready-to-use antibiotic for serious infections like pneumonia and urinary tract infections in hospitalized patients.
Questions about Urinary Tract Infections
Can a dipstick urinalysis reliably detect UTIs in babies under one year old?
Dipstick urinalysis has high specificity but low sensitivity for detecting UTIs in infants under 12 months, meaning it can rule in infection but often misses it.
Full answer →How accurate is a dipstick test for UTI in febrile infants under 12 months?
A dipstick test is fairly accurate for UTI in febrile infants under 12 months, with high specificity (91-99%) but moderate sensitivity (60-90%), meaning it rules in infection well but may miss some cases.
Full answer →What is the rate of breakthrough UTIs in children with VUR on antibiotics?
About 30.5% of children with VUR on antibiotic prophylaxis experience a breakthrough UTI, with higher risk in infants, high-grade reflux, and those with kidney scarring.
Full answer →How common is fluoroquinolone resistance in community-acquired E. coli causing urinary tract infections in Mexico?
Fluoroquinolone resistance in community-acquired E. coli causing UTIs in Mexico is high, with studies showing up to 68% of isolates are ESBL-producing and associated with high resistance rates.
Full answer →Does the FDA approved cefepime injection treat urinary tract infections in patients?
Yes, the FDA-approved cefepime injection is indicated for treating uncomplicated and complicated urinary tract infections caused by susceptible bacteria.
Full answer →What is the global resistance rate for fluoroquinolones in E. coli causing urinary tract infections?
A 2025 meta-analysis found the global fluoroquinolone resistance rate in E. coli causing UTIs is about 31%, with ciprofloxacin resistance at 30%.
Full answer →