N/A
Completed N=449
Transplant Regimen Adherence for Kidney Recipients by Engaging Information Technologies: The TAKE IT Trial
Source: ClinicalTrials.gov NCT03104868 ↗Enrolled (actual)
449
Serious AEs
0.9%
Results posted
Sep 2024
Primary outcomePrimary: Rx Pill Count — 0.26; 0.26 Probability of adherence (1/0)
Summary
The investigators will evaluate a technology-enabled strategy designed to promote medication adherence, routinely monitor regimen use, and mobilize appropriate transplant center resources to respond early to kidney transplant recipients demonstrating inadequate adherence.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Rx Pill Count |
0.26; 0.26 | — |
| SECONDARY Correct Medication Dosing Over Past 24 Hours (24 Hour Recall) |
0.89; 0.88 | — |
| SECONDARY Ask-12 |
18.4; 17.7 | — |
| SECONDARY Change in Estimated Glomerular Filtration Rate (eGFR), ml/Min/1.73m^2 |
-0.68; -0.76 | — |
| SECONDARY Re-hospitalization |
0.59; 0.59 | — |
Eligibility Criteria
Inclusion Criteria
- 1) age 21 or older
- 2) 5 weeks to 24 months post kidney transplant
- 3) English speaking
- 4) primarily responsible for administering own medication
- 5) owns a cell phone and comfortable receiving text messages
- 6) has access to and proficiency using internet in home
Exclusion Criteria
- any severe, uncorrectable vision, hearing or cognitive impairments
Data sourced from ClinicalTrials.gov (NCT03104868). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.