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N/A N=38 Randomized Single-blind Treatment

Gait Modification Treatments for Knee Pathology

Knee Injuries · Knee Osteoarthritis

Enrolled (actual)
38
Serious AEs
0.0%
Results posted
Aug 2021
Primary outcome: Primary: Change in Peak Knee Flexion Moment (%Bw*Ht) — 0.197; 0.018 %Bw*Ht — p=0.005

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Cutaneous Stimulation (Device); Knee Sleeve (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Stanford University
Primary completion
Jan 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Peak Knee Flexion Moment (%Bw*Ht)
0.197; 0.018 0.005 sig
SECONDARY
Change in Pain
1.476; -0.391
SECONDARY
Change in Function
4.48; 0.64
SECONDARY
Change in Symptoms
3.571; -0.781

Summary

The objective of this study is complete a longitudinal cross-over clinical study to investigate the effect of treatments for knee pathology, including cutaneous stimulation (skin vibration and soft knee brace), on locomotion tasks (i.e. walking, jogging, stair ascending and descending), muscle function, and pain/function.

Eligibility Criteria

Inclusion Criteria

  • Age 18-80
  • Ambulatory
  • Symptomatic knee pain ≥ 3/10 on most of the past 30 days
  • Prior ACL injury/surgery, meniscus injury/surgery, and/or physician-diagnosed medial compartment knee osteoarthritis (KL grade 1-3)
  • Agreement and ability to use provided interventions during the study period (suggested cumulative wear time during walking of 1-2 hr/day)
  • Committed to not starting any new therapies for knee condition during the trial, other than rescue pain medication.

Exclusion Criteria

  • Use of walking aid (e.g. cane, crutch, walker, or wheelchair)
  • BMI ≥ 35 kg/m2
  • Injection in the affected knee during the previous three months
  • Known neuropathy due to diabetes or other causes
  • Inability to provide informed consent
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03116230). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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