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N/A Completed N=38 Randomized Double-blind Basic Science

Non-Invasive Brain Stimulation and Substance Use

Source: ClinicalTrials.gov NCT03122587 ↗
Enrolled (actual)
38
Serious AEs
0.0%
Results posted
Mar 2020
Primary outcomePrimary: Change in Distress Tolerance (Mean Latency to Quit the PASAT-C) — 11.2; 9.8; 9.4 minutes

Summary

The will investigate the feasibility and effectiveness and initial efficacy of non-invasive transcranial alternating current stimulation (tACS) on distress tolerance and inhibitory control among treatment seeking substance users.

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Distress Tolerance (Mean Latency to Quit the PASAT-C)
11.2; 9.8; 9.4
PRIMARY
Change in Inhibitory Control (Mean D-prime on the Go/No-Go)
-0.6; 0.9; -0.3

Eligibility Criteria

Inclusion Criteria

  • Current Diagnostic and Statistical Manual of Mental Disorders (DSM-V) Substance Use Disorder
  • Current smoker
  • Abstinent from all substances (except nicotine) for at least the past 2 weeks

Exclusion Criteria

  • Current use of antiepileptic drugs and/or benzodiazepines
  • Less than 6 months since an electroconvulsive therapy (ECT) session
  • Current DSM-V Psychotic Disorder
  • Pregnancy and/or nursing
  • Ongoing or history of traumatic brain injury (TBI), reoccurring seizures, stroke, or brain tumors
  • Medical or neurological illness
  • Brain devices and/or implants
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03122587). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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