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N/A N=232 Randomized Single-blind Prevention

Vanderbilt ICU Recovery Program Pilot Trial

Intensive Care Unit Syndrome · Intensive Care Neurological Disorder · Intensive Care (ICU) Myopathy · Intensive Care Psychiatric Disorder (Diagnosis)

Enrolled (actual)
232
Serious AEs
0.0%
Results posted
Oct 2019
Primary outcome: Primary: Number of Components of the ICU Recovery Program Received — 2; 1 interventions

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
VANDERBILT ICU RECOVERY PROGRAM (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Vanderbilt University Medical Center
Primary completion
Oct 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Components of the ICU Recovery Program Received
2; 1
SECONDARY
Number of Participants With Same-hospital Readmission in the 30 Days After Hospital Discharge
16; 26
SECONDARY
Number of Participants Death or Readmission in the 30 Days After Hospital Discharge
20; 36
SECONDARY
Number Participants With Same-hospital Emergency Department Visits in the 30 Days After Hospital Discharge
1; 1
SECONDARY
Number of Same-hospital Outpatient Clinic Visits in the 30 Days After Hospital Discharge
14; 0

Summary

Every year, millions of Americans are admitted to the intensive care unit. Due to advances in critical care, mortality rates are decreasing, increasing the number of ICU survivors. Survivors of critical illness, however, often face physical, functional, and cognitive deficits that place them at risk for a cycle of re-hospitalization that frequently culminates in premature death. Moreover, post-ICU interventions may be resource-intensive and may be most cost-effective only in a subgroup of patients at highest risk. Whether a multi-disciplinary program to facilitate recovery from critical illness can prevent hospital readmission and improve quality of life among high-risk ICU survivors remains unknown. The primary aim of this pilot is to examine the feasibility of implementing a multidisciplinary ICU Recovery Program and the influence of such a program on process measures including contact with the ICU recovery team and attendance of ICU recovery clinic. The secondary aims are to compare the effect of an ICU Recovery Program on 30-day same-hospital readmission and other clinical outcomes.

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years
  • Admitted to the Medical Intensive Care Unit (MICU) at Vanderbilt University Medical Center for at least 48 hours
  • Estimated risk of 30-day same-hospital readmission greater than 15%
  • Not previously enrolled in the study.

Exclusion Criteria

  • Long-term residence at a skilled nursing facility
  • Long-term mechanical ventilation prior to admission
  • Solid organ or stem cell transplantation
  • Recorded primary residency > 200 miles from Vanderbilt
  • Comfort care only
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03124342). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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