N/A N=9 Neurosciences-Intensive Care Unit Electrical Stimulation
Intensive Care (ICU) Myopathy
Primary: Duration of Intubation — 10.22 days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=18 Early Insulin and Development of ARDS
Respiratory Distress Syndrome, Adult · Sepsis · Hyperglycemia
Primary: Plasma Levels of Free Fatty Acids, Tumor Necrosis Factor-α, Interleukin-6, and Von Willebrand Factor Antigen
N/A N=4,652 The Thai Surgical Intensive Care Study (Thai-SICU Study)
Complications of Surgical and Medical Care: General Terms · Adverse Reaction to Drug · Sequelae of External Causes of Morbidity and Mortality
Primary: Overall Mortality — 642 participants
N/A N=232 Vanderbilt ICU Recovery Program Pilot Trial
Intensive Care Unit Syndrome · Intensive Care Neurological Disorder · Intensive Care (ICU) Myopathy
Primary: Number of Components of the ICU Recovery Program Received — 2; 1 interventions
Phase 4 N=3,298 Stress Ulcer Prophylaxis in the Intensive Care Unit
Gastrointestinal Bleeding · Stress Ulcers
Primary: Mortality — 510; 499 Participants
N/A N=677 Unexpected Cardiac Arrest in Intensive Care Unit
Heart Arrest
Primary: Number of Patients With Unexpected Cardiac Arrest — 677; 30,722 Participants
N/A N=1,609 24 Hour Intensivist Coverage in the Medical Intensive Care Unit
Critically Ill
Primary: MICU Length of Stay — 52.8; 52.6 hours
N/A N=252 Impact on Mental, Physical, And Cognitive Functioning of a Critical Care sTay During the COVID-19 Pandemic
Covid19 · Critical Care · Postintensive Care Syndrome
Primary: World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) — 5; 13.5 units on a scale
N/A N=5,094 Second Survey of Intensive Care in India
Critical Illness
Primary: ICU Mortality — 1092 Participants
N/A N=22 Diagnosing Intensive Care Unit (ICU) Acquired Weakness
ICU Acquired Weakness
Primary: Peak Acceleration Measured in Extensor Carpi Radialis Longus — 0.476; 1.639; 0.541; 1.608 units of Gravity
N/A N=120 Treatment of Critical Illness Polyneuromyopathy
Acute Respiratory Failure
Primary: The Primary Outcome Variable for This Study Will be the Short Form of the Continuous Scale Physical Functional Performance Test (CS-PFP) Called the PFP-10 — 19.0; 20.9…
N/A N=15 Acupuncture for Sedation in the Intensive Care Unit (ICU)
Delirium · Respiratory Depression · Overmedication
Primary: Success of Blinding — 1; 1 Participants
N/A N=261 Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers
Intensive Care Unit Survivors · Informal Caregivers (Family and Friends)
Primary: Hospital Anxiety and Depression Scale Score — 16.6; 15.3; 15.6; 15.9 units on a scale (HADS summary score)
N/A N=82 Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock
Septic Shock · Fluid Therapy · Hypotension
Primary: Cumulative Fluid Administered — 4417; 4110 mL of study fluid
N/A N=7 A Randomized, Controlled Trial of Inspiratory Muscle Training (IMT)in the ICU and CCU
Critically Ill · Respiratory Failure
Primary: Safety and Feasibility of Inspiratory Muscle Training — 3; 3 Participants
N/A N=153 Improving the Recovery and Outcome Every Day After the ICU
Delirium · Alzheimer Disease
Primary: Cognitive Status Outcome at 6 Months — 0.24; 0.36; 0.21; 0.35 Z-score — p=0.747
N/A N=159 Decreasing Delirium Through Music in Critically Ill Older Adults
Intensive Care Unit Delirium · Pain · Anxiety
Primary: Days Free of Delirium and Coma — 2.5; 3 Delirium/coma-free days by day 7 — p=0.775
N/A N=80 Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Psychological Distress · Depression · Anxiety
Primary: Percent of Eligible Participants Who Provided Consent — 90 Participants
N/A N=83 Feasibility, Acceptability, and Barriers to Implementation of a Geriatrics Bundle in the ICU
Intensive Care Unit Syndrome
Primary: Feasibility of Bundle Delivery — 50 Participants
N/A N=40 Glycocalyx Damage in Critically Ill Patients
Critical Illness
Primary: Perfused Boundary Region (PBR) in One Week — 1.95; 1.97; 2.02 micrometer
Phase 3 N=566 The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study
Delirium · Impaired Cognition · Long Term Psychologic Disorders
Primary: Delirium/Coma-free Days (DCFDs) — 8; 8; 7 days
N/A N=34 Use of Neuromuscular Electrostimulation (NMES) for Treatment or Prevention of ICU-Associated Weakness
Intensive Care Unit · Muscle Weakness
Primary: Lower Extremity Strength, at Hospital Discharge, of 3 Bilateral Muscle Groups (Pretibial, Triceps Surae, and Quadriceps) Measured Via MMT Using a Composite Medical…
N/A N=296 Daily Checklists and Outcome in the Intensive Care Unit
Critical Illness
Primary: Empiric Antibiotic Duration — 3; 3 days — p=0.27
Phase 3 N=274 Hypovitaminosis D in Neurocritical Patients
Craniocerebral Trauma · Intracranial Aneurysm · Brain Neoplasms
Primary: Intent-to-treat Hospital Length-of-stay — 10.9; 9.1 days — p=0.2
N/A N=50 Pressure Injury Prevention in the ICU With Multi-Layer Foam Dressings
Pressure Incidence Prevention
Primary: User Friendliness of Both Sacrum and Heel (Left & Right) Dressings: Comfort, Conformability, Acceptability, the Handling at Application and Ease of Inspection of the…
Phase 4 N=47 Nicotine Replacement Therapy in the Intensive Care Unit
Delirium · Psychomotor Agitation · Substance Withdrawal Syndrome
Primary: 30-day Mortality — 9.5; 7.7 percentage of patients
N/A N=234 A Study to Evaluate ICU Simulation Experience in the Cardiothoracic Surgical Population to Reduce Post-operative Delirium
Post-Operative Delirium
Primary: Confusion Assessment Method for the ICU (CAM-ICU) — 4; 1 Participants
N/A N=73 Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS
Sepsis
Primary: Delta Curve Between Calculated GFR and GFR Measured by Iohexol at Baseline — 91.5; 88.3; 93.6; 90.0 ml/min/1.73m2 — p=<0.05
N/A N=5,834 European Mortality & Length Of Intensive Care Unit (ICU) Stay Evaluation (ELOISE)
Critical Illness
Primary: Vital Status at Hospital Discharge — 1232; 165 participants
Phase 1 N=8 Novel Arm Restraint in the Intensive Care Unit
Acute Respiratory Failure
Primary: Number of Treatment-Emergent Severe Adverse Events [Safety] — 0; 0 number of safety events