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N/A Completed N=310 Randomized Single-blind Treatment

Dulce Digital-Me: An Adaptive mHealth Intervention for Underserved Hispanics With Diabetes

Source: ClinicalTrials.gov NCT03130699 ↗
Enrolled (actual)
310
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcomePrimary: Glycosylated Hemoglobin (HbA1c) 6 Months After Enrollment — 8.17; 7.99; 8.44; 8.21 percentage — p=0.95

Summary

This study will compare Dulce Digital (i.e., the investigators' proven-effective combination of "one-size-fits-all" educational text messages and nurse monitoring of patient-transmitted blood glucose values) and Dulce Digital-Me (DD-Me), an adaptive/dynamic mHealth (mobile health) intervention that is tailored to individuals' needs and behavioral progress, in improving diabetes clinical control, adherence, and patient-provider communication in Hispanics - an at-risk, understudied population that experiences disparities in diabetes prevalence and outcomes. These striking disparities in the growing and aging US Hispanic population have taxed the US healthcare system, while significantly reducing quantity and quality of life for millions of individuals. By offering an innovative, scalable, and sustainable approach that seamlessly integrates several mHealth technologies into existing primary care team processes to improve the health of Hispanics (and eventually, other at-risk, underserved groups), DD-Me has strong potential to significantly impact public health.

Outcome Measures

OutcomeResultp-value
PRIMARY
Glycosylated Hemoglobin (HbA1c) 6 Months After Enrollment
8.17; 7.99; 8.44; 8.21 0.95
PRIMARY
Glycosylated Hemoglobin (HbA1c) 12 Months After Enrollment
8.29; 8.41; 8.83; 8.62 0.37
PRIMARY
Low-density Lipoprotein-cholesterol (LDL-C); 6 Months After Enrollment
90.27; 88.20; 102.93; 95.69 0.26
PRIMARY
Low-density Lipoprotein-cholesterol (LDL-C); 12 Months After Enrollment
97.85; 94.10; 92.04; 93.08 0.90
PRIMARY
Systolic Blood Pressure (SBP); 6 Months From Enrollment
126.70; 124.84; 124.78; 124.81 0.21
PRIMARY
Systolic Blood Pressure (SBP); 12 Months From Enrollment
125.10; 122.82; 124.13; 123.47 0.30
SECONDARY
Patient-Provider Communication; 6 Months From Enrollment
4.18; 4.04; 4.28; 4.16 0.90
SECONDARY
Patient-Provider Communication; 12 Months From Enrollment
4.09; 3.99; 4.16; 4.06 0.72
SECONDARY
Patient Blood Glucose Monitoring; 6 Months From Enrollment
5.07; 5.62; 5.11; 5.37 0.61
SECONDARY
Patient Blood Glucose Monitoring; 12 Months From Enrollment
5.08; 4.77; 5.15; 4.94 0.49
SECONDARY
Participated in Aerobic Exercise; 6 Months From Enrollment
5.46; 5.29; 5.49; 5.41 0.96
SECONDARY
Participated in Aerobic Exercise; 12 Months From Enrollment
5.11; 5.12; 4.72; 4.94 0.64
SECONDARY
Participated in Strength Exercise; 6 Months From Enrollment
20; 11; 10; 21 0.87
SECONDARY
Participated in Strength Exercise; 12 Months From Enrollment
12; 9; 8; 17 0.58
SECONDARY
Participated in Flexibility Exercise; 6 Months From Enrollment
44; 39; 31; 70 0.25
SECONDARY
Participated in Flexibility Exercise; 12 Months From Enrollment
29; 34; 15; 49 0.11
SECONDARY
Healthy Eating Behaviors; 6 Months From Enrollment
50.12; 50.48; 49.41; 49.98 0.76
SECONDARY
Healthy Eating Behaviors; 12 Months From Enrollment
51.04; 50.24; 50.67; 50.43 0.05
SECONDARY
Diabetes Distress; 6 Months From Enrollment
2.16; 2.12; 2.16; 2.14 0.63
SECONDARY
Diabetes Distress; 12 Months From Enrollment
1.96; 2.23; 2.07; 2.16 0.63
SECONDARY
Adherence to Refills and Medications Scale (ARMS) - Patient-reported Outcome; 6 Months From Enrollment
17.23; 16.31; 16.12; 16.22 0.002 sig
SECONDARY
Adherence to Refills and Medications Scale (ARMS) - Patient-reported Outcome; 12 Months From Enrollment
16.68; 16.25; 15.85; 16.08 0.008 sig

Eligibility Criteria

Inclusion Criteria

  • Self-identified Hispanic/Latino
  • 18 years or older
  • Registered patient of a Neighborhood Healthcare Clinic
  • Diagnosed with T2DM (Type 2 Diabetes Mellitus)
  • HbA1c ≥ 8.0% and/or SBP ≥ 160 mmHg, and/or LDL-C ≥ 100 mg/dL in the last 30 days

Exclusion Criteria

  • Severe illness precluding regular clinic visits
  • Pregnant or lactating
  • Type 1 or gestational diabetes
  • Lack of minimal literacy
  • Plans to relocate
  • Severe auditory or visual problems
  • Primary language other than Spanish or English
  • Unwilling to carry a mobile phone
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03130699). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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