N/A
N=230
Intervention Comparative Effectiveness for Adult Cognitive Training
Cognitive Aging
Bottom Line
View on ClinicalTrials.gov: NCT03141281 ↗Enrolled (actual)
230
Serious AEs
0.0%
Results posted
Jun 2021
Primary outcome: Primary: Fraud Detection Post Training — 90.42; 85.84; 84.88; 84.32 % confidence fraudulent item is fraud
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- BrainHQ (Behavioral); Rise of Nations (Behavioral); IADL Training (Behavioral); Active Control (Behavioral)
- Age
- Older Adult · 65+ yrs
- Sex
- All
- Sponsor
- Florida State University
- Primary completion
- Sep 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Fraud Detection Post Training |
90.42; 85.84; 84.88; 84.32; 85.91; 86.34 | — |
| PRIMARY Driving Simulator Hazard Perception Post Training |
-0.06; 0.26; 0.02; 0.12; 0.09; -0.10 | — |
| PRIMARY Self-reported Difficulty With Instrumental Activities of Daily Living (IADLs) Post Training |
0.31; 0.26; 0.38; 0.39; 0.35; 0.23 | — |
| PRIMARY Speed of Processing Post Training |
0.09; 0.03; -0.03; 0.01; 0.34; 0.16 | — |
| PRIMARY Knowledge About Driving Post Training |
1.49; 1.53; 2.28; 1.36 | — |
| PRIMARY Knowledge About Finances and Fraud Post Training |
1.65; 1.62; 2.24; 1.54 | — |
| PRIMARY Fraud Detection at One Year |
90.88; 87.78; 86.30; 84.86; 87.79; 87.17 | — |
| PRIMARY Driving Simulator Hazard Perception at One Year |
0.02; 0.31; -0.06; 0.07; 0.11; 0.34 | — |
| PRIMARY Self-reported Difficulty With Instrumental Activities of Daily Living (IADLs) at One Year |
0.27; 0.16; 0.10; 0.36; 0.38; 0.22 | — |
| PRIMARY Speed of Processing at One Year |
0.10; 0.12; 0.07; 0.01; 0.22; 0.36 | — |
| PRIMARY Knowledge About Driving at One Year |
1.36; 1.46; 1.59; 1.62 | — |
| PRIMARY Knowledge About Finances and Fraud at One Year |
1.53; 1.95; 1.78; 1.55 | — |
| PRIMARY Driving Simulator Average Speed Post Training |
12.46; 13.46; 12.71; 13.12; 13.25; 12.88 | — |
| PRIMARY Driving Simulator Max Brake Compression Post Training |
0.98; 1.00; 0.99; 1.00; 0.99; 0.91 | — |
| PRIMARY Driving Simulator Average Lane Position Post Training |
-0.43; -0.35; -0.41; -0.40; -0.41; -0.39 | — |
| PRIMARY Driving Simulator Average Speed at One Year |
12.71; 13.76; 13.04; 12.96; 13.36; 14.08 | — |
| PRIMARY Driving Simulator Max Brake Compression at One Year |
0.99; 1.00; 0.99; 1.00; 0.98; 1.00 | — |
| PRIMARY Driving Simulator Average Lane Position at One Year |
-0.41; -0.35; -0.46; -0.41; -0.40; -0.35 | — |
| PRIMARY Useful Field of View Post Training |
225.84; 229.08; 228.55; 212.14; 170.04; 217.47 | — |
| PRIMARY Digit Symbol Substitution Test Post Training |
46.45; 45.36; 44.04; 43.71; 48.90; 48.66 | — |
| PRIMARY Useful Field of View at One Year |
229.38; 199.58; 206.54; 211.90; 200.85; 158.65 | — |
| PRIMARY Digit Symbol Substitution Test at One Year |
47.02; 45.65; 44.84; 43.58; 48.36; 47.65 | — |
| SECONDARY Technology Proficiency Post Training |
0.16; 0.21; -0.03; -0.13; 0.24; 0.16 | — |
| SECONDARY Technology Proficiency at One Year |
0.11; 0.35; 0.06; -0.21; 0.20; 0.50 | — |
| SECONDARY Numeracy Post Training |
2.41; 2.49; 2.38; 2.39; 2.45; 2.66 | — |
| SECONDARY Numeracy at One Year |
2.36; 2.65; 2.47; 2.52; 2.40; 2.76 | — |
| SECONDARY Reasoning Ability Post Training |
0.10; 0.14; -0.18; -0.02; 0.08; 0.13 | — |
| SECONDARY Reasoning Ability at One Year |
0.10; 0.14; -0.10; 0.05; -0.04; 0.08 | — |
| SECONDARY Memory Ability Post Training |
-0.01; 0.04; 0.04; 0.15; 0.23; 0.05 | — |
| SECONDARY Memory Ability at One Year |
0.06; 0.10; 0.16; 0.25; 0.19; 0.21 | — |
| SECONDARY Miami Instrumental Activities of Daily Living Task Post Training |
3.17; 2.78; 2.67; 2.81; 3.19; 3.23 | — |
| SECONDARY Miami Instrumental Activities of Daily Living Task at One Year |
3.18; 3.03; 2.78; 2.79; 3.09; 3.26 | — |
Summary
The study will compare the effect of broad and directed (narrow) technology-based training on basic perceptual and cognitive abilities in older adults and on the performance of simulated tasks of daily living including driving and fraud avoidance.
Eligibility Criteria
Inclusion Criteria
- Age 65 years and above
- Plans to stay in the Tallahassee, Leon County area for the next year
- Valid driver's license and drives at least once a month
- Adequate cognitive ability assessed via telephone interview using the Wechsler Memory Scale III with story A score >6 or story B score >4.
Exclusion Criteria
- Terminal illness with life expectancy less than 12 months
- Reports or exhibits a disabling visual condition assessed as the inability to read printed material
- Reports or exhibits a disabling speech hearing and comprehension condition assessed by inability to hear and comprehend the screener's instructions
- Reports or exhibits a disabling speech production condition assessed as the inability to respond with comprehensible English speech to the screener's queries
- Reports or exhibits a disabling psychomotor condition assessed as the inability to use a keyboard and pointing device
- Has completed the AARP driver training course
- Has played the Rise of Nations video game
- Has trained with Posit Science's "BrainHQ"
- Has trained on the Mind Frontiers video game.
Data sourced from ClinicalTrials.gov (NCT03141281). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.