Clinical Trial Search

Primary: Knowledge of Memory Aging Questionnaire-Revised — 19.8; 19.5 units on a scale

Primary: Percentage of Trials Correct On Working Memory Test — 87.69; 91.57; 88.01; 91.68 percentage of correct trials — p=>0.05

Primary: Initial Eye-movements Toward Target and Distractor Shapes Measured by an Eye-tracker — 3.8; 4.4; 3.6; 4.5 percentage of first saccades

Primary: Changes in the Breakfast Game Performance: Number of Tables Set Score — 1.61; 1.43 score on a scale (change)

Primary: Complutense Verbal Learning Test (TAVEC) - Memory — 0.94; -0.81; 1.65; -0.31 units on a scale

Primary: Change Executive Language Functions (Category Verbal Fluency) — 5; -1 Number of Fluent Words within 60 seconds

Primary: Rate of Participant Long Term Care Planning for Alzheimer's Dementia/Memory Loss — 173 Participants — p=.6539

Primary: Change From Baseline in California Verbal Learning Task Score — 3.04; 5.17; 4.22; 7.04 score on a scale

Primary: Total Number of Goals Improved to Criterion on the Canadian Occupational Performance Measure (COPM) — 50; 19.6; 50; 32.6 percentage of untrained goals improved — p=0.03

Primary: Change in Depression Severity (Measured by Montgomery Asberg Depression Rating Scale) — 25.26; 1.03; 13.78; 1.08 score on a scale — p=< 0.025

Primary: Functional Magnetic Resonance Imaging (fMRI) Changes in Response to Estrogen and Aging - Dorsolateral Pre-frontal Cortex (DLPFC) — 455.8; -214.4; -348.1; 90.1 linear…

Primary: Working Memory — 0.86; 0.04 digits recalled

Primary: Change in Hippocampal-dependent Learning — -.00369; .00404 learning rate (proportion correct/trial) — p=<.05

Primary: Change in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) — -0.89; 0.55 score

Primary: Magnetic Resonance Spectroscopy — 0.41; -0.29 ppm — p=0.05

Primary: Auditory Memory Attention Index — 89.0; 94.3 standard score units — p=<0.01

Primary: Magnetic Resonance Spectroscopy (MRS) Will Measure a Change in Cerebral Energy Function in Brain Tissue — .011; .007; .009; .006 Difference in metabolite amplitude

Primary: Neuropsychological Status (i.e., Cognitive Functioning) — 0.008; .484; -.084; -.482 z-score composites of cognitive domains — p=0.001

Primary: Differences in Error Rates on the NBack Task Between Real and Sham Stimulation Trials — -0.79; -0.1 incorrect responses

Primary: Percentage of Participants Completing the Study — 90 Percentage of participants

Primary: Object Location Touchscreen Task (Version C) Free Recall Total Error — 121.498; 99.77 centimeters — p=.300

Primary: Change in NIH Toolbox Fluid Cognition Composite Score — 4.7; 6.1 units on a scale

Primary: Neuropsychological Performance in Neuropsychological Test: Verbal Learning Memory Test (VLMT) — 57.2; 57.2 score on a scale — p=0.74

Primary: Hamilton Depression Rating Scale. — 8.09 units on a scale

Primary: CRM Performance During First Sim Scenario Assessed by Ottawa Global Rating Scale (GRS) — -0.299 Pearson correlation coefficient — p=0.039

Primary: FCI Score at Follow-up — 147.3; 164.0; 123.3; 150.8 points awarded for correct items

Primary: Acute Effect of a rTMS Session on the Performance for a Working Memory Task, as Measured by Accuracy (in Percentage) — 50.43; 55.42; 83.93; 46.49 percentage of accuracy

Primary: Leisure Activities Questionnaire Activities Sum — 1.45; 4.45; 11.25 score on a scale — p=<0.05

Primary: Change in Cognitive Function as Measured Using the Extended Mini Mental State Exam — 0.58 Change on a scale

Primary: Memory Composite Score — -0.11; -0.14; -0.13; -0.12 Z-score — p=0.50