N/A
N=208
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial
HIV Infections
Bottom Line
View on ClinicalTrials.gov: NCT03149757 ↗Enrolled (actual)
208
Serious AEs
0.0%
Results posted
Jul 2023
Primary outcome: Primary: Visual Analog Scale (VAS) of Self-Reported Antiretroviral Adherence — 85.71; 85.53 Unit on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- YouTHrive (Behavioral); Information-only Control (Behavioral)
- Age
- Pediatric, Adult · 15+ yrs
- Sex
- All
- Sponsor
- University of Minnesota
- Primary completion
- May 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Visual Analog Scale (VAS) of Self-Reported Antiretroviral Adherence |
85.71; 85.53 | — |
| SECONDARY Percentage of Participants With Undetectable HIV Viral Load |
56; 43 | — |
Summary
YouTHrive (YT) is a two-arm randomized control trial (RCT) to test the efficacy of an adapted version of the Thrive With Me (TWM) intervention for youth living with HIV (YLWH). In the RCT, intervention participants will have access to the full YouTHrive (YT) website- a mobile-enhanced private social networking website aimed at improving medication adherence for YLWH. The investigators will enroll up to 60 YLWH for formative work on YT, and 300 YLWH (15-24 years old) of all genders living in eight cities and randomize them to either the intervention condition or control condition. Assessments will be collected at baseline and 5-month follow-up.
Eligibility Criteria
Inclusion Criteria
- 15-24 years of age at the enrollment visit;
- HIV-positive status;
- Residing in Chicago, Houston, NYC, Philadelphia, Atlanta, Tampa, or Raleigh/Durham/Chapel Hill areas and available to meet in-person or virtually with SRV staff for visits at baseline and 5-month follow-up assessment;
- English-speaking (since the intervention will be in English);
- Anticipated continuous internet access and SMS messaging for the intervention period (approximately 5 months);
- Not enrolled in another ART adherence intervention research study at the time of screening;
- Has or is willing to create an e-mail address to use during the study period;
- Did not attend an iTech Youth Advisory Board (YAB) or Youth Advisory Council (YAC) meeting where the YouTHrive study was presented or YouTHrive study materials were discussed.
Exclusion Criteria
- Is younger than 15 years old or older than 24 years old at the enrollment visit;
- does not have an HIV-positive status;
- Does not reside in Chicago, Houston, NYC, Philadelphia, Atlanta, Tampa, or Raleigh/Durham/Chapel Hill areas and not available to meet with SRV staff for visits at baseline, and 5-month follow-up assessment;
- Does not speak English;
- Does not anticipate having continuous internet access and SMS messaging for the intervention period (approximately 5 months);
- Is enrolled in another ART adherence intervention research study at the time of screening;
- Does not have or is not willing to create an e-mail address to use during the study period;
- Is a member of an iTech Youth Advisory Board (YAB) or Youth Advisory Council (YAC).
Participants who are or become pregnant during the study period will not be excluded.
Data sourced from ClinicalTrials.gov (NCT03149757). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.