N/A Completed N=29 Randomized Treatment

Initiating Substance Use Disorder Treatment for Hospitalized Opioid Use Disorder Patients.

Opioid Use Disorder

Source: ClinicalTrials.gov NCT03212794 ↗

Enrolled (actual)

Serious AEs

52.0%

Results posted

Dec 2023

Primary outcomePrimary: Treatment Retention — 5; 5 Participants — p==0.87

Summary

The purpose of this 24-week study is to evaluate the impact of recovery coach intervention on rates of treatment retention, illicit opioid use, and readmission among hospitalized patients newly initiated on buprenorphine or methadone compared to the control intervention.

Outcome Measures

Outcome	Result	p-value
PRIMARY Treatment Retention	5; 5	=0.87
SECONDARY Readmissions	6; 5	=0.82
SECONDARY Days to Treatment Discontinuation	59.11; 26.71	=0.92
SECONDARY Days to Hospital Readmission	72.57; 67.67	=0.85

Eligibility Criteria

Inclusion Criteria

English speaking, adults aged 18-75
Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) diagnosis of opioid use disorder, severe, actively using illicit opioids until the time of hospitalization
Have a working telephone
Can identify at least 2 individuals who can act as points of contact following discharge from the hospital
Willing to engage in treatment (either a psychosocial treatment program AND/OR medication treatment with methadone or buprenorphine)

Exclusion Criteria

Liver function test >3x upper normal limit
Pregnant
Psychotic disorder, active suicidality or homicidality
Condition likely to be terminal in 24 weeks such as cancer
Unable to perform consent due to mental status
Engaged in substance abuse treatment in the last month prior to admission

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03212794). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.