N/A
N=29
Initiating Substance Use Disorder Treatment for Hospitalized Opioid Use Disorder Patients.
Opioid-use Disorder
Bottom Line
View on ClinicalTrials.gov: NCT03212794 ↗Enrolled (actual)
29
Serious AEs
52.0%
Results posted
Dec 2023
Primary outcome: Primary: Treatment Retention — 5; 5 Participants — p==0.87
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Recovery coach (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Brigham and Women's Hospital
- Primary completion
- Dec 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Treatment Retention |
5; 5 | =0.87 |
| SECONDARY Readmissions |
6; 5 | =0.82 |
| SECONDARY Days to Treatment Discontinuation |
59.11; 26.71 | =0.92 |
| SECONDARY Days to Hospital Readmission |
72.57; 67.67 | =0.85 |
Summary
The purpose of this 24-week study is to evaluate the impact of recovery coach intervention on rates of treatment retention, illicit opioid use, and readmission among hospitalized patients newly initiated on buprenorphine or methadone compared to the control intervention.
Eligibility Criteria
Inclusion Criteria
- English speaking, adults aged 18-75
- Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) diagnosis of opioid use disorder, severe, actively using illicit opioids until the time of hospitalization
- Have a working telephone
- Can identify at least 2 individuals who can act as points of contact following discharge from the hospital
- Willing to engage in treatment (either a psychosocial treatment program AND/OR medication treatment with methadone or buprenorphine)
Exclusion Criteria
- Liver function test >3x upper normal limit
- Pregnant
- Psychotic disorder, active suicidality or homicidality
- Condition likely to be terminal in 24 weeks such as cancer
- Unable to perform consent due to mental status
- Engaged in substance abuse treatment in the last month prior to admission
Data sourced from ClinicalTrials.gov (NCT03212794). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.