Combination buprenorphine and psychotherapy linked to highest remission rates in opioid dependence patients
Combining buprenorphine and therapy boosts remission rates for opioid dependence
This retrospective cohort study analyzed 18,047 adults aged 18–45 with opioid dependence across 112 U.S. health systems. The combination of …
In a large study, pairing buprenorphine with psychotherapy showed the strongest link to remission from opioid use disorder compared to no tr…
Peer navigators provide direct, informational, and facilitation support for OUD during community re-entry
What kind of help do people need most when leaving jail with opioid addiction?
A Connecticut RCT sub-study of 108 criminal legal-involved adults with OUD characterized peer navigator support during community re-entry. P…
When leaving jail, opioid recovery hinges on practical help like rides to appointments and paperwork support, not just medical advice.
Pilot study examines salivary adiponectin receptor expression in opioid-exposed neonates
How does a mother's opioid use affect her baby's growth signals?
This observational pilot cohort compared salivary adiponectin receptor 1 expression and growth measurements in neonates born at ≥34 weeks' g…
Doctors are investigating how a mother's opioid use during pregnancy might change a newborn's growth signals and body fat levels.
Report estimates state-level economic costs of opioid use disorder and fatal overdose
Report estimates state-level economic costs of opioid use disorder and overdose
A report estimated state-level economic costs of opioid use disorder and fatal opioid overdose in the United States. Specific numerical find…
A new report estimates the economic costs of opioid use disorder and fatal overdoses for every state in the United States in 2017.
In adult ED encounters, clinician engagement with EHR-based SDOH data was rare but higher in opioid use disorder cases.
Did reviewing social data in the ER actually change how doctors treated opioid use disorder patients?
This cross-sectional study of 17,103 adult emergency department encounters examined clinician engagement with electronic health record-based…
Doctors reviewed social data more often for opioid use disorder patients, yet this action did not increase medication treatments or fix raci…
Pennsylvania report examines controlled substance prescribing patterns before fatal overdoses
What prescriptions did people have before dying from an overdose in Pennsylvania?
An observational report from Pennsylvania analyzed controlled substance prescribing patterns preceding fatal overdoses involving opioids, st…
A new Pennsylvania report maps the controlled substance prescriptions people received before dying from an overdose involving opioids or sti…
Protocol outlines target trial emulation for bipolar disorder treatments in patients with opioid use disorder
Study protocol compares bipolar disorder medications for people with opioid use disorder
This protocol describes a planned target trial emulation study using population-level administrative data from British Columbia and Ontario,…
People with bipolar disorder and opioid use disorder face higher risks, but a new plan will compare how well different medications work for …
Case series describes possible severe withdrawal syndrome in 23 patients using illegal opioids in Pittsburgh
Doctors report possible severe withdrawal in 23 patients using illegal opioids in Pittsburgh
A case series of 23 patients in Pittsburgh hospitals who used illegally manufactured opioids reported a possible severe withdrawal syndrome.…
Doctors in Pittsburgh report 23 patients using illegal opioids experienced possible severe withdrawal, highlighting a potential risk that ne…
Lifetime opioid overdose reported by 55% of pregnant individuals with OUD in buprenorphine treatment study
What puts pregnant women with opioid addiction at highest risk for overdose?
A descriptive analysis of baseline data from a multisite RCT of 140 pregnant individuals with OUD receiving buprenorphine found 55% reported…
Pregnant women in opioid treatment face high overdose risk if they have used heroin, experienced trauma, or rely on others for money.
National trends show rising Hepatitis C and opioid use disorder rates in pregnant women at delivery
Study finds rising Hepatitis C and opioid disorder rates among pregnant women in the U.S.
An observational study of pregnant women at delivery hospitalization in the United States from 2000-2015 found significant increases in both…
Hepatitis C and opioid use disorder rates rose significantly among U.S. pregnant women delivering in hospitals between 2000 and 2015.
Telemedicine-Assisted Buprenorphine Induction Non-Inferior to Standard Care for OUD Retention
Can starting addiction treatment by video work as well as in-person visits?
A randomized controlled non-inferiority trial in 138 adults with opioid use disorder in India found telemedicine-assisted buprenorphine indu…
Patients starting opioid addiction treatment via video calls stay in care just as well as those with in-person visits during the first week.
tDCS shows craving reduction in male methadone patients; machine learning algorithm achieves 94% diagnostic accuracy
Small study tests brain stimulation and AI for opioid addiction in men
A small RCT in 36 male methadone maintenance patients and 24 healthy controls found that active tDCS groups showed significant craving reduc…
A machine learning algorithm identified opioid addiction with 94.3% accuracy in a small study, and brain stimulation reduced cravings in men…