N/A N=92 Randomized Single-blind Treatment

Optimizing Physical Activity Outcomes After Total Knee Arthroplasty

Total Knee Arthroplasty · Osteoarthritis

Bottom Line

View on ClinicalTrials.gov: NCT03226106 ↗

Enrolled (actual)

Serious AEs

12.0%

Results posted

Oct 2024

Primary outcome: Primary: Free-living Daily Step Count — 6947; 6339 step count — p=0.024

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Physical Activity Behavior Intervention (Behavioral); Attention Control (Other)
Age: Adult, Older Adult · 50+ yrs
Sex: All
Sponsor: VA Office of Research and Development
Primary completion: May 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Free-living Daily Step Count	6947; 6339	0.024 sig
SECONDARY 30-Second Chair-Stand Test W14	13; 12	0.584
SECONDARY 30-Second Chair-Stand Test W38	14; 14	0.724
SECONDARY Six-Minute Walk Test W14	433; 434	0.547
SECONDARY Six-Minute Walk Test W38	452; 451	0.716
SECONDARY Timed Up-and-Go Test W14	9.8; 9.4	0.946
SECONDARY Timed Up-and-Go Test W38	9.1; 9.0	0.906
SECONDARY Western Ontario and McMaster Universities Osteoarthritis Index W14	18; 21	0.873
SECONDARY Western Ontario and McMaster Universities Osteoarthritis Index W38	13; 22	0.241
SECONDARY Veterans RAND 12-Item Health Survey Physical Component W14	43; 39	0.223
SECONDARY Veterans RAND 12-Item Health Survey Physical Component W38	43; 41	0.388
SECONDARY Veterans RAND 12-Item Health Survey Mental Component W14	54; 52	0.88
SECONDARY Veterans RAND 12-Item Health Survey Mental Component W38	55; 51	0.85
SECONDARY Free-living Daily Step Count W38	7287; 6855	0.101

Summary

Although total knee arthroplasty is an effective intervention for decreasing knee pain and improving physical function, physical activity levels remain low up to a year after surgery. This study will use mobile-health technology to deliver an intervention designed to improve physical activity behavior for Veterans recovering from total knee arthroplasty. The study will assess the effectiveness of using behavior-change intervention as a supplement to conventional rehabilitation to improve physical activity. The intervention will be delivered using home-based tablet computers for Veterans to have remote interaction with the researcher and real-time physical activity feedback from a wrist-worn activity sensor.

Eligibility Criteria

Inclusion Criteria

Veteran
Planned unilateral total knee arthroplasty

Exclusion Criteria

Severe non-surgical limb pain (pain >5/10 on non-surgical limb with walking)
Unstable orthopedic, neurologic, or pulmonary condition that limits function
Unstable cardiac condition
Uncontrolled hypertension
Uncontrolled diabetes
Acute systemic infection
Active cancer treatment
Recent stroke (within 2 years)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03226106). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.