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N/A Completed N=317 Randomized Double-blind Treatment

Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia

Fibromyalgia · Postoperative Pain · Muscular Diseases · Musculoskeletal Disease
Source: ClinicalTrials.gov NCT03268421 ↗
Enrolled (actual)
317
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcomePrimary: Functional Disability Inventory — 25.78; 24.10; 25.96; 21.83 score on a scale

Summary

This study evaluated whether Fibromyalgia Integrative Training program for Teens (FIT Teens), a combined cognitive behavioral therapy and neuromuscular exercise training program is more effective in reducing disability in adolescents with Juvenile Fibromyalgia compared to cognitive behavioral therapy (CBT) alone or a graded aerobic exercise (GAE) program alone. One third of participants received the FIT Teens training; one third received CBT training; and one third of participants received the GAE training.

Outcome Measures

OutcomeResultp-value
PRIMARY
Functional Disability Inventory
25.78; 24.10; 25.96; 21.83; 21.65; 24.70
SECONDARY
Pain Intenstiy
5.71; 5.93; 5.88; 5.29; 5.41; 5.44

Eligibility Criteria

Inclusion Criteria

  • Juvenile Fibromyalgia diagnosis by pediatric rheumatologist or pain physician and confirmed by 2010 American College of Rheumatology (ACR) criteria modified for pediatric use
  • Functional Disability Score ≥ 13, indicating at least moderate disability
  • Average pain intensity in the past week ≥ 4 on a 0 -10 cm Visual Analog Scale
  • Stable medications prior to enrollment

Exclusion Criteria

  • Comorbid rheumatic disease (e.g. juvenile arthritis, systemic lupus erythematous)
  • Untreated major psychiatric diagnoses (e.g. bipolar disorder, psychoses, symptoms of major depression) or documented developmental delay
  • Any medical condition determined by their physician to be a contraindication for physical exercise
  • Taking opioid pain medication
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03268421). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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