N/A N=30 Randomized Treatment

Functional Resistance Training to Improve Knee Function After ACL Reconstruction

Anterior Cruciate Ligament Injury

Bottom Line

View on ClinicalTrials.gov: NCT03282565 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2022

Primary outcome: Primary: Quadriceps Muscle Strength — .674; .398; .279 Nm/Kg

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Functional Resistance Training with Brace (Other); Control (Other); Functional Resistance Training with Elastic Band (Other)
Age: Pediatric, Adult · 14+ yrs
Sex: All
Sponsor: University of Michigan
Primary completion: Dec 2020

Outcome Measures

Outcome	Result	p-value
PRIMARY Quadriceps Muscle Strength	.674; .398; .279	—
SECONDARY Quadriceps Voluntary Activation	73.19; 69.55; 68.29	—
SECONDARY Knee Flexion Angle Symmetry	3.230; 0.556; 0.846	—
SECONDARY Knee Moment Symmetry	.0144; 0.132; -0.042	—

Summary

The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury and reconstruction can be improved with functional resistance training.

Eligibility Criteria

Inclusion Criteria

aged 14-40 years
suffered an acute, complete ACL rupture
willingness to participate in testing and follow-up as outlined in the protocol
English-speaking

Exclusion Criteria

inability to provide written informed consent
female subjects who are pregnant or are planning to become pregnant
previous ACL injury
previous surgery to either knee
bony fracture accompanying ACL injury
patients who experienced a knee dislocation;
patients who are contraindicated for transcranial magnetic stimulation (e.g., metal implants in head, unexplained recurrent headaches, history of seizures, epileptogenic drugs, active psychiatric illness, etc.).

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03282565). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.