N/A Completed N=142 Randomized Single-blind Treatment

Five, Plus Nuts and Beans for Kidneys

Chronic Kidney Disease · Hypertension

Source: ClinicalTrials.gov NCT03299816 ↗

Enrolled (actual)

142

Serious AEs

9.9%

Results posted

Jun 2023

Primary outcomePrimary: Change in Urinary Albumin Excretion From Baseline to 4 Months — -28.6; -5.6 mg/g — p=0.17

Summary

This Five, Plus Nuts and Beans for Kidneys Study is a single center, randomized controlled trial with 2 parallel arms testing the hypothesis that delivery of nutritional advice to adopt a Dietary Approaches to Stop Hypertension (DASH)-like diet and $30/week worth of fruits, vegetables, nuts and beans tailored to personal choices and availability in neighborhood stores, will reduce kidney damage in African Americans with hypertension and chronic kidney disease.

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Urinary Albumin Excretion From Baseline to 4 Months	-28.6; -5.6	0.17
SECONDARY Change in Systolic Blood Pressure From Baseline to 4 Months	-1.4; 0.9	0.36
SECONDARY Change in Systolic Blood Pressure From Baseline to 12 Months	1.5; -1.6	0.33
SECONDARY Change in Urinary Albumin Excretion From Baseline to 12 Months	-11.5; -1.4	0.61

Eligibility Criteria

Inclusion Criteria

Self-identified African American race
Age 21 years or older
Clinical diagnosis of hypertension and have a urine Albumin-Creatinine Ratio (ACR) of ≥30 mg/g with or without estimated Glomerular Filtration Rate (GFR) 30-59 ml/min/1.73m2.
Must be under regular care with their Johns Hopkins Community Physicians (JHCP) or Johns Hopkins Outpatient Center (JHOC) physician (seen within the past 12 months).
Must have a systolic blood pressure of 9%).
Patients with a serum potassium >4.6 milliequivalent (mEq) /L45
Urine ACR ≥ 1,000 mg/g

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03299816). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.