N/A
N=1,822
Caregiver Outcomes of Alzheimer's Disease Screening
Alzheimer Disease
Bottom Line
View on ClinicalTrials.gov: NCT03300180 ↗Enrolled (actual)
1,822
Serious AEs
14.1%
Results posted
May 2025
Primary outcome: Primary: Short Form Health Survey (SF-36) — 48.4; 47.8; 48.8; 44.7 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Collaborative Dementia Care Program (Behavioral); Screening Only (Other)
- Age
- Older Adult · 65+ yrs
- Sex
- All
- Sponsor
- Indiana University
- Primary completion
- Sep 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Short Form Health Survey (SF-36) |
48.4; 47.8; 48.8; 44.7; 44.8; 44.4 | — |
| SECONDARY Depressive Symptoms |
2.8; 2.6; 2.9; 2.4; 2.3; 2.2 | — |
| SECONDARY Anxiety Symptoms |
1.8; 1.6; 1.7; 1.7; 1.8; 1.8 | — |
| SECONDARY Caregiving Preparedness |
3.0; 2.9; 2.9 | — |
| SECONDARY Caregiving Self Efficacy |
79.1; 79.3; 79.6 | — |
Summary
This study will measure the risks and benefits of early screening of Alzheimer's disease. Early diagnosis through screening may enhance the family member's transition to a family caregiver and reduce caregiver burden by providing an opportunity for the family member to learn about the syndrome, receive interventions, and to prepare for their new care giving role.
Eligibility Criteria
Inclusion Criteria
Patients
- 65 years or older
- At least one visit to primary care practice within past 24 months
- Ability to provide informed consent
- Ability to communicate in English
Family Members
- 21 years or older
- Identified by the patient as the person most likely to provide them care if needed.*
- Lives with the patient or lives within a 50 mile radius.
- Ability to provide informed consent.
- Ability to communicate in English
Exclusion Criteria
Patients
- Has a diagnosis of AD as determined by ICD-10 code.
- Evidence of a prescription for a cholinesterase inhibitors or memantine.
- Has serious mental illness such as bipolar or schizophrenia as determined by ICD-10 code
- Permanent resident of a nursing facility
- Already seen by the Healthy Aging Brain Care Program
Family Member
- Is a non-family member who is not a legal Healthcare Power of Attorney
- Has serious mental illness such as bipolar or schizophrenia as determined by ICD-10 code
- Has a diagnosis of AD as determined by ICD-10 code.
Data sourced from ClinicalTrials.gov (NCT03300180). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.