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N/A N=92 Randomized Supportive Care

Psychological Intervention for Caregivers of Patients Undergoing Stem Cell Transplant

Cancer

Enrolled (actual)
92
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Feasibility of the Intervention (Feasibility Description Below) — 36 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
CARE (Other); Standard Transplant Care (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Massachusetts General Hospital
Primary completion
Apr 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Feasibility of the Intervention (Feasibility Description Below)
36
SECONDARY
Compare Caregiver Quality of Life (QOL) as Measured by the Caregiver Oncology QOL (CarGOQOL) Questionnaire Between the Study Arms
81.22; 70.96
SECONDARY
Compare Caregiving Burden (CRA) Between the Study Arms
46.95; 55.06
SECONDARY
Compare Caregiver Anxiety Using Hospital Anxiety and Depression Scale (HADS) Between the Study Arms
3.62; 7.22
SECONDARY
Compare Caregiver Self-efficacy Using the Cancer Self-Efficacy Scale-Transplant (CASE-t) Between the Study Arms
156.20; 147.06
SECONDARY
Compare Perceived Coping Skills (MOCS) Between the Study Arms
36.54; 28.02

Summary

This research study is evaluating the impact of a psychological intervention on the quality of life and mood of caregivers of patients undergoing stem cell transplant.

Eligibility Criteria

Inclusion Criteria

  • Adult caregivers (≥18 years) of patients undergoing autologous or allogeneic HCT at MGH, and they must attend the HCT consent visit with the patient.
  • A relative or a friend who either lives with the patient or has in-person contact with him or her at least twice per week and is identified as the primary caregiver for transplant.
  • Ability to speak English or able to complete questionnaires with minimum assistance of an interpreter.

Exclusion Criteria

  • Significant uncontrolled psychiatric or other co-morbid disease, which the primary oncologist believes prohibits the ability to participate in study procedures
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03328663). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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