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Phase 2 Completed N=51 Randomized Single-blind Treatment

Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?

Quality of Recovery · Same Day Surgery · Nausea and Vomiting, Postoperative · vaginal prolapse
Source: ClinicalTrials.gov NCT03338400 ↗
Enrolled (actual)
51
Serious AEs
0.0%
Results posted
May 2019
Primary outcomePrimary: Questionnaire: Quality of Recovery 40 — 174; 167 score on a scale

Summary

To the investigators knowledge there are no studies in the literature evaluating the effect of Dexamethasone administration on patients undergoing outpatient vaginal prolapse surgeries.

Outcome Measures

OutcomeResultp-value
PRIMARY
Questionnaire: Quality of Recovery 40
174; 167
SECONDARY
Nausea, Vomiting
2; 2
SECONDARY
Urinary Tract Infections
1; 2
SECONDARY
Readmissions
4; 1
SECONDARY
Pain Level
6.04; 4.77

Eligibility Criteria

Inclusion Criteria

  • Women over the age of 18
  • Women scheduled for vaginal POP reconstructive surgery with or without concomitant anti-incontinence procedure and with or without hysterectomy
  • ASA class 1-2

Exclusion Criteria

  • Daily use of steroids, antiemetics in the month prior to surgery
  • Chronic pain requiring daily opioid treatment
  • History of allergy/intolerance to Dexamethasone
  • ASA class 3
  • Numerical Pain score of more than 4 at baseline
  • Renal/Liver disease
  • Diabetes mellitus
  • Pregnancy
  • Inability to answer questionnaires
  • Any systemic infections
  • Immuno compromised status
  • Patients with planned overnight stay
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03338400). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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